Predictors of cognition in adults with HIV: Implications for nursing practice and research

Pariya L. Fazeli, Janice C. Marceaux, David E. Vance, Larry Slater, C. Ann Long

Research output: Contribution to journalArticle

Abstract

The objective of this study was to identify predictors of cognitive performance among adults with HIV. Participants completed demographic, psychosocial, and mental and physical health questionnaires as well as cognitive measures of speed of processing, psychomotor ability and visuomotor coordination, attention and working memory, reasoning, and executive function. Hierarchical regression analyses were used to examine predictors of cognitive performance for each cognitive measure. Possible predictors included age, gender, socioeconomic status, Wide Range Achievement Test 3 Reading score (quality of education), social networks score, hardiness score, mood disturbance score, medical problems composite score, psychoactive drug use composite score, HIV chronicity, CD4+ lymphocyte cell count, and HIV medication usage. Model 1 examined demographic factors, and model 2 examined the contribution of the remaining variables on cognitive performance. Results revealed that several factors were predictive of cognitive functioning, with the individual regression models for each measure explaining 8% to 48% of the variability in performance. Overall, this study posits that among adults with HIV, the most consistent predictors of poorer cognition included older age, poorer reading ability, more depressed mood, CD4+ lymphocyte cell count less than 200, and lack of HIV medication usage. Results suggest that those aging with HIV are subject to decreases in cognitive functioning.

Original languageEnglish (US)
Pages (from-to)36-50
Number of pages15
JournalThe Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses
Volume43
Issue number1
DOIs
StatePublished - Feb 2011

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Nursing Research
Cognition
HIV
CD4 Lymphocyte Count
Aptitude
Reading
Demography
Psychotropic Drugs
Executive Function
Short-Term Memory
Social Class
Social Support
Practice (Psychology)
Mental Health
Regression Analysis
Education

ASJC Scopus subject areas

  • Clinical Neurology
  • Endocrine and Autonomic Systems
  • Medical–Surgical
  • Surgery

Cite this

Predictors of cognition in adults with HIV : Implications for nursing practice and research. / Fazeli, Pariya L.; Marceaux, Janice C.; Vance, David E.; Slater, Larry; Long, C. Ann.

In: The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, Vol. 43, No. 1, 02.2011, p. 36-50.

Research output: Contribution to journalArticle

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