Potassium Channels: Symmetric, Selective, and Sensitive

Dirk Trauner

Research output: Contribution to journalReview article

Abstract

Crystallized and elucidated: Our understanding of the basic functions of ion channels-the selective guidance of ions through cell membranes and the control of this process by "gates"-is derived to a large extent from the contributions of Roderick MacKinnon, who was awarded a Nobel Prize this year for his work. The picture shows the X-ray crystal structure of the prokaryotic potassium channel KcsA (blue: K+ ions, red: carbonyl groups of the peptide backbone and water molecules).

Original languageEnglish (US)
Pages (from-to)5671-5675
Number of pages5
JournalAngewandte Chemie - International Edition
Volume42
Issue number46
DOIs
StatePublished - Dec 1 2003

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Potassium Channels
Ions
Cell membranes
Ion Channels
Crystal structure
X rays
Peptides
Molecules
Water
prokaryotic potassium channel

Keywords

  • Ion channels
  • Membranes
  • Neurobiology
  • Protein structures
  • Structure elucidation

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Potassium Channels : Symmetric, Selective, and Sensitive. / Trauner, Dirk.

In: Angewandte Chemie - International Edition, Vol. 42, No. 46, 01.12.2003, p. 5671-5675.

Research output: Contribution to journalReview article

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