Poly(vinyl alcohol) as versatile biomaterial for potential biomedical applications

Gaio Paradossi, Francesca Cavalieri, Ester Chiessi, Chiara Spagnoli, Mary Cowman

Research output: Contribution to journalArticle

Abstract

In this paper, we present some new case examples where the chemical versatility of poly (vinyl alcohol) (PVA) can be used for potential biomedical applications. PVA, the polymeric material used for designing new nanostructured devices, is water soluble, biocompatible and has excellent physical properties. We point out the possibility of obtaining wall-to-wall chemical hydrogels as well as microgels without diminishing the biocompatibility available in the starting PVA material. Injectability is another important factor to take into account in controlled drug delivery for gene therapy. In this respect, in this paper, established and more innovative methods are prospected in order to obtain particles with dimensions suitable for these applications.

Original languageEnglish (US)
Pages (from-to)687-691
Number of pages5
JournalJournal of Materials Science: Materials in Medicine
Volume14
Issue number8
DOIs
StatePublished - Aug 1 2003

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Hydrogels
Biocompatible Materials
Biomaterials
Genetic Therapy
Alcohols
Controlled drug delivery
Gene therapy
Equipment and Supplies
Water
Biocompatibility
Pharmaceutical Preparations
Physical properties
Polymers

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Chemical Engineering(all)

Cite this

Poly(vinyl alcohol) as versatile biomaterial for potential biomedical applications. / Paradossi, Gaio; Cavalieri, Francesca; Chiessi, Ester; Spagnoli, Chiara; Cowman, Mary.

In: Journal of Materials Science: Materials in Medicine, Vol. 14, No. 8, 01.08.2003, p. 687-691.

Research output: Contribution to journalArticle

Paradossi, Gaio ; Cavalieri, Francesca ; Chiessi, Ester ; Spagnoli, Chiara ; Cowman, Mary. / Poly(vinyl alcohol) as versatile biomaterial for potential biomedical applications. In: Journal of Materials Science: Materials in Medicine. 2003 ; Vol. 14, No. 8. pp. 687-691.
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