Point-of-care oral-based diagnostics

Rw Hart, Mg Mauk, C. Liu, X. Qiu, Ja Thompson, D. Chen, Daniel Malamud, Wr Abrams, Hh Bau

Research output: Contribution to journalArticle

Abstract

Many of the target molecules that reside in blood are also present in oral fluids, albeit at lower concentrations. Oral fluids are, however, relatively easy and safe to collect without the need for specialized equipment and training. Thus, oral fluids provide convenient samples for medical diagnostics. Recent advances in lab-on-a-chip technologies have made minute, fully integrated diagnostic systems practical for an assortment of point-of-care tests. Such systems can perform either immunoassays or molecular diagnostics outside centralized laboratories within time periods ranging from minutes to an hour. The article briefly reviews recent advances in devices for point-of-care testing with a focus on work that has been carried out by the authors as part of a NIH program.

Original languageEnglish (US)
Pages (from-to)745-752
Number of pages8
JournalOral Diseases
Volume17
Issue number8
DOIs
StatePublished - Nov 2011

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Point-of-Care Systems
Equipment and Supplies
Molecular Pathology
Immunoassay
Technology

Keywords

  • Lab-on-a-chip
  • Microfluidics
  • Oral-based diagnostics
  • Point-of-care testing

ASJC Scopus subject areas

  • Dentistry(all)
  • Otorhinolaryngology

Cite this

Hart, R., Mauk, M., Liu, C., Qiu, X., Thompson, J., Chen, D., ... Bau, H. (2011). Point-of-care oral-based diagnostics. Oral Diseases, 17(8), 745-752. https://doi.org/10.1111/j.1601-0825.2011.01808.x

Point-of-care oral-based diagnostics. / Hart, Rw; Mauk, Mg; Liu, C.; Qiu, X.; Thompson, Ja; Chen, D.; Malamud, Daniel; Abrams, Wr; Bau, Hh.

In: Oral Diseases, Vol. 17, No. 8, 11.2011, p. 745-752.

Research output: Contribution to journalArticle

Hart, R, Mauk, M, Liu, C, Qiu, X, Thompson, J, Chen, D, Malamud, D, Abrams, W & Bau, H 2011, 'Point-of-care oral-based diagnostics', Oral Diseases, vol. 17, no. 8, pp. 745-752. https://doi.org/10.1111/j.1601-0825.2011.01808.x
Hart R, Mauk M, Liu C, Qiu X, Thompson J, Chen D et al. Point-of-care oral-based diagnostics. Oral Diseases. 2011 Nov;17(8):745-752. https://doi.org/10.1111/j.1601-0825.2011.01808.x
Hart, Rw ; Mauk, Mg ; Liu, C. ; Qiu, X. ; Thompson, Ja ; Chen, D. ; Malamud, Daniel ; Abrams, Wr ; Bau, Hh. / Point-of-care oral-based diagnostics. In: Oral Diseases. 2011 ; Vol. 17, No. 8. pp. 745-752.
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