Point detection of bacterial and viral pathogens using oral samples

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Oral samples, including saliva, offer an attractive alternative to serum or urine for diagnostic testing. This is particularly true for point-of-use detection systems. The various types of oral samples that have been reported in the literature are presented here along with the wide variety of analytes that have been measured in saliva and other oral samples. The paper focuses on utilizing point-detection of infectious disease agents, and presents work from our group on a rapid test for multiple bacterial and viral pathogens by monitoring a series of targets. It is thus possible in a single oral sample to identify multiple pathogens based on specific antigens, nucleic acids, and host antibodies to those pathogens. The value of such a technology for detecting agents of bioterrorism at remote sites is discussed.

Original languageEnglish (US)
Title of host publicationOptics and Photonics in Global Homeland Security IV
Volume6945
DOIs
StatePublished - 2008
EventOptics and Photonics in Global Homeland Security IV - Orlando, FL, United States
Duration: Mar 17 2008Mar 20 2008

Other

OtherOptics and Photonics in Global Homeland Security IV
CountryUnited States
CityOrlando, FL
Period3/17/083/20/08

Fingerprint

pathogens
Pathogens
saliva
Bioterrorism
Nucleic acids
Antigens
Antibodies
urine
nucleic acids
antigens
infectious diseases
antibodies
serums
Monitoring
Testing

Keywords

  • Bacteria
  • Microfluidic
  • Oral
  • Pathogen
  • Pathogens
  • Point-of-care (POC)
  • Saliva
  • Up-Converting Phosphor (UCP)
  • Viral

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Malamud, D. (2008). Point detection of bacterial and viral pathogens using oral samples. In Optics and Photonics in Global Homeland Security IV (Vol. 6945). [69450C] https://doi.org/10.1117/12.779160

Point detection of bacterial and viral pathogens using oral samples. / Malamud, Daniel.

Optics and Photonics in Global Homeland Security IV. Vol. 6945 2008. 69450C.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Malamud, D 2008, Point detection of bacterial and viral pathogens using oral samples. in Optics and Photonics in Global Homeland Security IV. vol. 6945, 69450C, Optics and Photonics in Global Homeland Security IV, Orlando, FL, United States, 3/17/08. https://doi.org/10.1117/12.779160
Malamud D. Point detection of bacterial and viral pathogens using oral samples. In Optics and Photonics in Global Homeland Security IV. Vol. 6945. 2008. 69450C https://doi.org/10.1117/12.779160
Malamud, Daniel. / Point detection of bacterial and viral pathogens using oral samples. Optics and Photonics in Global Homeland Security IV. Vol. 6945 2008.
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