Plasmonic enhancement of a whispering-gallery-mode biosensor for single nanoparticle detection in aqueous solution

S. I. Shopova, R. Rajmangal, S. Holler, S. Arnold

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We describe and demonstrate a physical mechanism that substantially enhances the label-free sensitivity of a Whispering-Gallery-Mode biosensor for the detection of individual nanoparticles in aqueous solution. It involves the interaction of dielectric nanoparticle in an equatorial carousel orbit with a plasmonic nanoparticle bound on the orbital path. As a 60 nm dielectric particle parks on plasmonic hot spots we observe frequency shifts that are considerably enhanced consistent with a simple reactive model. Using the same model the label free detection of a single bovine serum albumin (BSA) molecule is projected.

Original languageEnglish (US)
Title of host publicationPhotonic Microdevices/Microstructures for Sensing IV
Volume8376
DOIs
StatePublished - 2012
EventPhotonic Microdevices/Microstructures for Sensing IV - Baltimore, MD, United States
Duration: Apr 26 2012Apr 27 2012

Other

OtherPhotonic Microdevices/Microstructures for Sensing IV
CountryUnited States
CityBaltimore, MD
Period4/26/124/27/12

Fingerprint

Whispering Gallery Modes
Whispering gallery modes
Biosensor
whispering gallery modes
Plasmonics
bioinstrumentation
Biosensors
Nanoparticles
Enhancement
aqueous solutions
nanoparticles
augmentation
Labels
equatorial orbits
Hot Spot
Bovine Serum Albumin
albumins
serums
frequency shift
Orbits

Keywords

  • biosensing
  • plasmonic enhancement
  • whispering-gallery-mode

ASJC Scopus subject areas

  • Applied Mathematics
  • Computer Science Applications
  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

Cite this

Shopova, S. I., Rajmangal, R., Holler, S., & Arnold, S. (2012). Plasmonic enhancement of a whispering-gallery-mode biosensor for single nanoparticle detection in aqueous solution. In Photonic Microdevices/Microstructures for Sensing IV (Vol. 8376). [837605] https://doi.org/10.1117/12.920614

Plasmonic enhancement of a whispering-gallery-mode biosensor for single nanoparticle detection in aqueous solution. / Shopova, S. I.; Rajmangal, R.; Holler, S.; Arnold, S.

Photonic Microdevices/Microstructures for Sensing IV. Vol. 8376 2012. 837605.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Shopova, SI, Rajmangal, R, Holler, S & Arnold, S 2012, Plasmonic enhancement of a whispering-gallery-mode biosensor for single nanoparticle detection in aqueous solution. in Photonic Microdevices/Microstructures for Sensing IV. vol. 8376, 837605, Photonic Microdevices/Microstructures for Sensing IV, Baltimore, MD, United States, 4/26/12. https://doi.org/10.1117/12.920614
Shopova SI, Rajmangal R, Holler S, Arnold S. Plasmonic enhancement of a whispering-gallery-mode biosensor for single nanoparticle detection in aqueous solution. In Photonic Microdevices/Microstructures for Sensing IV. Vol. 8376. 2012. 837605 https://doi.org/10.1117/12.920614
Shopova, S. I. ; Rajmangal, R. ; Holler, S. ; Arnold, S. / Plasmonic enhancement of a whispering-gallery-mode biosensor for single nanoparticle detection in aqueous solution. Photonic Microdevices/Microstructures for Sensing IV. Vol. 8376 2012.
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