Physicochemical characterization and in vivo evaluation of amorphous and partially crystalline calcium phosphate coatings fabricated on Ti-6Al-4V implants by the plasma spray method

Estevam A. Bonfante, Lukasz Witek, Nick Tovar, Marcelo Suzuki, Charles Marin, Rodrigo Granato, Paulo Coelho

Research output: Contribution to journalArticle

Abstract

Objective. To characterize the topographic and chemical properties of 2 bioceramic coated plateau root form implant surfaces and evaluate their histomorphometric differences at 6 and 12 weeks in vivo. Methods. Plasma sprayed hydroxyapatite (PSHA) and amorphous calcium phosphate (ACP) surfaces were characterized by scanning electron microscopy (SEM), interferometry (IFM), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FT-IR). Implants were placed in the radius epiphysis, and the right limb of dogs provided implants that remained for 6 weeks, and the left limb provided implants that remained 12 weeks in vivo. Thin sections were prepared for bone-to-implant contact (BIC) and bone-area-fraction occupancy (BAFO) measurements (evaluated by Friedman analysis P 0.05). Results. Significantly, higher S a (P 0.03) and S q (P 0.02) were observed for ACP relative to PSHA. Chemical analysis revealed significantly higher HA, calcium phosphate, and calcium pyrophosphate for the PSHA surface. BIC and BAFO measurements showed no differences between surfaces. Lamellar bone formation in close contact with implant surfaces and within the healing chambers was observed for both groups. Conclusion. Given topographical and chemical differences between PSHA and ACP surfaces, bone morphology and histomorphometric evaluated parameters showed that both surfaces were osseoconductive in plateau root form implants.

Original languageEnglish (US)
Article number603826
JournalInternational Journal of Biomaterials
DOIs
StatePublished - 2012

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Phosphate coatings
Calcium phosphate
Bone
Crystalline materials
Plasmas
Coatings
Durapatite
Hydroxyapatite
Calcium Pyrophosphate
Bioceramics
calcium phosphate
Interferometry
Chemical properties
Fourier transform infrared spectroscopy
Calcium
X ray diffraction
Scanning electron microscopy
Chemical analysis

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering

Cite this

@article{9961ba2c91d84caa9ff7e74ed32e3b1a,
title = "Physicochemical characterization and in vivo evaluation of amorphous and partially crystalline calcium phosphate coatings fabricated on Ti-6Al-4V implants by the plasma spray method",
abstract = "Objective. To characterize the topographic and chemical properties of 2 bioceramic coated plateau root form implant surfaces and evaluate their histomorphometric differences at 6 and 12 weeks in vivo. Methods. Plasma sprayed hydroxyapatite (PSHA) and amorphous calcium phosphate (ACP) surfaces were characterized by scanning electron microscopy (SEM), interferometry (IFM), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FT-IR). Implants were placed in the radius epiphysis, and the right limb of dogs provided implants that remained for 6 weeks, and the left limb provided implants that remained 12 weeks in vivo. Thin sections were prepared for bone-to-implant contact (BIC) and bone-area-fraction occupancy (BAFO) measurements (evaluated by Friedman analysis P 0.05). Results. Significantly, higher S a (P 0.03) and S q (P 0.02) were observed for ACP relative to PSHA. Chemical analysis revealed significantly higher HA, calcium phosphate, and calcium pyrophosphate for the PSHA surface. BIC and BAFO measurements showed no differences between surfaces. Lamellar bone formation in close contact with implant surfaces and within the healing chambers was observed for both groups. Conclusion. Given topographical and chemical differences between PSHA and ACP surfaces, bone morphology and histomorphometric evaluated parameters showed that both surfaces were osseoconductive in plateau root form implants.",
author = "Bonfante, {Estevam A.} and Lukasz Witek and Nick Tovar and Marcelo Suzuki and Charles Marin and Rodrigo Granato and Paulo Coelho",
year = "2012",
doi = "10.1155/2012/603826",
language = "English (US)",
journal = "International Journal of Biomaterials",
issn = "1687-8787",
publisher = "Hindawi Publishing Corporation",

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TY - JOUR

T1 - Physicochemical characterization and in vivo evaluation of amorphous and partially crystalline calcium phosphate coatings fabricated on Ti-6Al-4V implants by the plasma spray method

AU - Bonfante, Estevam A.

AU - Witek, Lukasz

AU - Tovar, Nick

AU - Suzuki, Marcelo

AU - Marin, Charles

AU - Granato, Rodrigo

AU - Coelho, Paulo

PY - 2012

Y1 - 2012

N2 - Objective. To characterize the topographic and chemical properties of 2 bioceramic coated plateau root form implant surfaces and evaluate their histomorphometric differences at 6 and 12 weeks in vivo. Methods. Plasma sprayed hydroxyapatite (PSHA) and amorphous calcium phosphate (ACP) surfaces were characterized by scanning electron microscopy (SEM), interferometry (IFM), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FT-IR). Implants were placed in the radius epiphysis, and the right limb of dogs provided implants that remained for 6 weeks, and the left limb provided implants that remained 12 weeks in vivo. Thin sections were prepared for bone-to-implant contact (BIC) and bone-area-fraction occupancy (BAFO) measurements (evaluated by Friedman analysis P 0.05). Results. Significantly, higher S a (P 0.03) and S q (P 0.02) were observed for ACP relative to PSHA. Chemical analysis revealed significantly higher HA, calcium phosphate, and calcium pyrophosphate for the PSHA surface. BIC and BAFO measurements showed no differences between surfaces. Lamellar bone formation in close contact with implant surfaces and within the healing chambers was observed for both groups. Conclusion. Given topographical and chemical differences between PSHA and ACP surfaces, bone morphology and histomorphometric evaluated parameters showed that both surfaces were osseoconductive in plateau root form implants.

AB - Objective. To characterize the topographic and chemical properties of 2 bioceramic coated plateau root form implant surfaces and evaluate their histomorphometric differences at 6 and 12 weeks in vivo. Methods. Plasma sprayed hydroxyapatite (PSHA) and amorphous calcium phosphate (ACP) surfaces were characterized by scanning electron microscopy (SEM), interferometry (IFM), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FT-IR). Implants were placed in the radius epiphysis, and the right limb of dogs provided implants that remained for 6 weeks, and the left limb provided implants that remained 12 weeks in vivo. Thin sections were prepared for bone-to-implant contact (BIC) and bone-area-fraction occupancy (BAFO) measurements (evaluated by Friedman analysis P 0.05). Results. Significantly, higher S a (P 0.03) and S q (P 0.02) were observed for ACP relative to PSHA. Chemical analysis revealed significantly higher HA, calcium phosphate, and calcium pyrophosphate for the PSHA surface. BIC and BAFO measurements showed no differences between surfaces. Lamellar bone formation in close contact with implant surfaces and within the healing chambers was observed for both groups. Conclusion. Given topographical and chemical differences between PSHA and ACP surfaces, bone morphology and histomorphometric evaluated parameters showed that both surfaces were osseoconductive in plateau root form implants.

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