Abstract
Mechanized nanoparticles (MNPs) consisting of supramolecular machines attached to the surface of mesoporous silica nanoparticles are designed to release encapsulated guest molecules controllably under pH activation. The molecular machines are comprised of cucurbit[6]uril (CB[6]) rings that encircle tethered trisammonium stalks and can be tuned to respond under specific pH conditions through chemical modification of the stalks. Luminescence spectroscopy demonstrates that the MNPs are able to contain guest molecules within nanopores at neutral pH levels and then release them once the pH is lowered or raised.
Original language | English (US) |
---|---|
Pages (from-to) | 12912-12914 |
Number of pages | 3 |
Journal | Journal of the American Chemical Society |
Volume | 131 |
Issue number | 36 |
DOIs | |
State | Published - Sep 16 2009 |
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ASJC Scopus subject areas
- Catalysis
- Chemistry(all)
- Biochemistry
- Colloid and Surface Chemistry
Cite this
pH clock-operated mechanized nanoparticles. / Angelos, Sarah; Khashab, Niveen M.; Yang, Ying Wei; Trabolsi, Ali; Khatib, Hussam A.; Stoddart, J. Fraser; Zink, Jeffrey I.
In: Journal of the American Chemical Society, Vol. 131, No. 36, 16.09.2009, p. 12912-12914.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - pH clock-operated mechanized nanoparticles
AU - Angelos, Sarah
AU - Khashab, Niveen M.
AU - Yang, Ying Wei
AU - Trabolsi, Ali
AU - Khatib, Hussam A.
AU - Stoddart, J. Fraser
AU - Zink, Jeffrey I.
PY - 2009/9/16
Y1 - 2009/9/16
N2 - Mechanized nanoparticles (MNPs) consisting of supramolecular machines attached to the surface of mesoporous silica nanoparticles are designed to release encapsulated guest molecules controllably under pH activation. The molecular machines are comprised of cucurbit[6]uril (CB[6]) rings that encircle tethered trisammonium stalks and can be tuned to respond under specific pH conditions through chemical modification of the stalks. Luminescence spectroscopy demonstrates that the MNPs are able to contain guest molecules within nanopores at neutral pH levels and then release them once the pH is lowered or raised.
AB - Mechanized nanoparticles (MNPs) consisting of supramolecular machines attached to the surface of mesoporous silica nanoparticles are designed to release encapsulated guest molecules controllably under pH activation. The molecular machines are comprised of cucurbit[6]uril (CB[6]) rings that encircle tethered trisammonium stalks and can be tuned to respond under specific pH conditions through chemical modification of the stalks. Luminescence spectroscopy demonstrates that the MNPs are able to contain guest molecules within nanopores at neutral pH levels and then release them once the pH is lowered or raised.
UR - http://www.scopus.com/inward/record.url?scp=70349106429&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70349106429&partnerID=8YFLogxK
U2 - 10.1021/ja9010157
DO - 10.1021/ja9010157
M3 - Article
C2 - 19705840
AN - SCOPUS:70349106429
VL - 131
SP - 12912
EP - 12914
JO - Journal of the American Chemical Society
JF - Journal of the American Chemical Society
SN - 0002-7863
IS - 36
ER -