pH clock-operated mechanized nanoparticles

Sarah Angelos, Niveen M. Khashab, Ying Wei Yang, Ali Trabolsi, Hussam A. Khatib, J. Fraser Stoddart, Jeffrey I. Zink

    Research output: Contribution to journalArticle

    Abstract

    Mechanized nanoparticles (MNPs) consisting of supramolecular machines attached to the surface of mesoporous silica nanoparticles are designed to release encapsulated guest molecules controllably under pH activation. The molecular machines are comprised of cucurbit[6]uril (CB[6]) rings that encircle tethered trisammonium stalks and can be tuned to respond under specific pH conditions through chemical modification of the stalks. Luminescence spectroscopy demonstrates that the MNPs are able to contain guest molecules within nanopores at neutral pH levels and then release them once the pH is lowered or raised.

    Original languageEnglish (US)
    Pages (from-to)12912-12914
    Number of pages3
    JournalJournal of the American Chemical Society
    Volume131
    Issue number36
    DOIs
    StatePublished - Sep 16 2009

    Fingerprint

    Nanoparticles
    Clocks
    Molecules
    Nanopores
    Chemical modification
    Silicon Dioxide
    Luminescence
    Chemical activation
    Silica
    Spectroscopy
    Spectrum Analysis
    cucurbit(6)uril

    ASJC Scopus subject areas

    • Catalysis
    • Chemistry(all)
    • Biochemistry
    • Colloid and Surface Chemistry

    Cite this

    Angelos, S., Khashab, N. M., Yang, Y. W., Trabolsi, A., Khatib, H. A., Stoddart, J. F., & Zink, J. I. (2009). pH clock-operated mechanized nanoparticles. Journal of the American Chemical Society, 131(36), 12912-12914. https://doi.org/10.1021/ja9010157

    pH clock-operated mechanized nanoparticles. / Angelos, Sarah; Khashab, Niveen M.; Yang, Ying Wei; Trabolsi, Ali; Khatib, Hussam A.; Stoddart, J. Fraser; Zink, Jeffrey I.

    In: Journal of the American Chemical Society, Vol. 131, No. 36, 16.09.2009, p. 12912-12914.

    Research output: Contribution to journalArticle

    Angelos, S, Khashab, NM, Yang, YW, Trabolsi, A, Khatib, HA, Stoddart, JF & Zink, JI 2009, 'pH clock-operated mechanized nanoparticles', Journal of the American Chemical Society, vol. 131, no. 36, pp. 12912-12914. https://doi.org/10.1021/ja9010157
    Angelos S, Khashab NM, Yang YW, Trabolsi A, Khatib HA, Stoddart JF et al. pH clock-operated mechanized nanoparticles. Journal of the American Chemical Society. 2009 Sep 16;131(36):12912-12914. https://doi.org/10.1021/ja9010157
    Angelos, Sarah ; Khashab, Niveen M. ; Yang, Ying Wei ; Trabolsi, Ali ; Khatib, Hussam A. ; Stoddart, J. Fraser ; Zink, Jeffrey I. / pH clock-operated mechanized nanoparticles. In: Journal of the American Chemical Society. 2009 ; Vol. 131, No. 36. pp. 12912-12914.
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