pH clock-operated mechanized nanoparticles

Sarah Angelos, Niveen M. Khashab, Ying Wei Yang, Ali Trabolsi, Hussam A. Khatib, J. Fraser Stoddart, Jeffrey I. Zink

Research output: Contribution to journalArticle

Abstract

Mechanized nanoparticles (MNPs) consisting of supramolecular machines attached to the surface of mesoporous silica nanoparticles are designed to release encapsulated guest molecules controllably under pH activation. The molecular machines are comprised of cucurbit[6]uril (CB[6]) rings that encircle tethered trisammonium stalks and can be tuned to respond under specific pH conditions through chemical modification of the stalks. Luminescence spectroscopy demonstrates that the MNPs are able to contain guest molecules within nanopores at neutral pH levels and then release them once the pH is lowered or raised.

Original languageEnglish (US)
Pages (from-to)12912-12914
Number of pages3
JournalJournal of the American Chemical Society
Volume131
Issue number36
DOIs
StatePublished - Sep 16 2009

Fingerprint

Nanoparticles
Clocks
Molecules
Nanopores
Chemical modification
Silicon Dioxide
Luminescence
Chemical activation
Silica
Spectroscopy
Spectrum Analysis
cucurbit(6)uril

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

Angelos, S., Khashab, N. M., Yang, Y. W., Trabolsi, A., Khatib, H. A., Stoddart, J. F., & Zink, J. I. (2009). pH clock-operated mechanized nanoparticles. Journal of the American Chemical Society, 131(36), 12912-12914. https://doi.org/10.1021/ja9010157

pH clock-operated mechanized nanoparticles. / Angelos, Sarah; Khashab, Niveen M.; Yang, Ying Wei; Trabolsi, Ali; Khatib, Hussam A.; Stoddart, J. Fraser; Zink, Jeffrey I.

In: Journal of the American Chemical Society, Vol. 131, No. 36, 16.09.2009, p. 12912-12914.

Research output: Contribution to journalArticle

Angelos, S, Khashab, NM, Yang, YW, Trabolsi, A, Khatib, HA, Stoddart, JF & Zink, JI 2009, 'pH clock-operated mechanized nanoparticles', Journal of the American Chemical Society, vol. 131, no. 36, pp. 12912-12914. https://doi.org/10.1021/ja9010157
Angelos S, Khashab NM, Yang YW, Trabolsi A, Khatib HA, Stoddart JF et al. pH clock-operated mechanized nanoparticles. Journal of the American Chemical Society. 2009 Sep 16;131(36):12912-12914. https://doi.org/10.1021/ja9010157
Angelos, Sarah ; Khashab, Niveen M. ; Yang, Ying Wei ; Trabolsi, Ali ; Khatib, Hussam A. ; Stoddart, J. Fraser ; Zink, Jeffrey I. / pH clock-operated mechanized nanoparticles. In: Journal of the American Chemical Society. 2009 ; Vol. 131, No. 36. pp. 12912-12914.
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