Periodontitis and the end-stage renal disease patient receiving hemodialysis maintenance therapy.

Ronald Craig, Peter Kotanko

Research output: Contribution to journalArticle

Abstract

Atherosclerotic complications, including myocardial infarction and stroke, are highly prevalent and associated with increased systemic inflammation in patients who have end-stage renal disease (ESRD) and are receiving renal hemodialysis maintenance therapy. In the general population, an increasing body of evidence suggests periodontitis can contribute to systemic inflammation and may contribute to atherosclerotic complications. In addition, results of recent interventional trials suggest effective periodontal therapy may decrease systemic inflammation as well as endothelial dysfunction, an early predictor of atherosclerotic complications. Because moderate-to-severe periodontitis appears to be highly prevalent in the renal hemodialysis population, effective periodontal therapy may reduce systemic inflammation and thereby become a treatment consideration for this population. This article will acquaint dental practitioners with ESRD and the association between systemic inflammation and mortality. Also discussed are the possible contributions of destructive periodontal diseases to systemic inflammation and the dental management of patients receiving renal replacement therapies.

Original languageEnglish (US)
JournalCompendium of continuing education in dentistry (Jamesburg, N.J. : 1995)
Volume30
Issue number8
StatePublished - Oct 2009

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Periodontitis
Chronic Kidney Failure
Renal Dialysis
Inflammation
Tooth
Therapeutics
Population
Kidney
Renal Replacement Therapy
Periodontal Diseases
Stroke
Myocardial Infarction
Mortality

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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