Peptide and protein recognition by designed molecules

Mark W. Peczuh, Andrew Hamilton

Research output: Contribution to journalArticle

Abstract

At present, there is a growing interest in understanding and manipulating protein-protein interactions due to their central importance in many biological processes. This article details current strategies for binding protein surfaces with emphasis on the use of designed molecules. Examples are given that indicate the great promise in the design of small molecules to bind protein surfaces.

Original languageEnglish (US)
Pages (from-to)2479-2494
Number of pages16
JournalChemical Reviews
Volume100
Issue number7
DOIs
StatePublished - Jul 2000

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Peptides
Molecules
Carrier Proteins
Membrane Proteins
Proteins

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Peptide and protein recognition by designed molecules. / Peczuh, Mark W.; Hamilton, Andrew.

In: Chemical Reviews, Vol. 100, No. 7, 07.2000, p. 2479-2494.

Research output: Contribution to journalArticle

Peczuh, Mark W. ; Hamilton, Andrew. / Peptide and protein recognition by designed molecules. In: Chemical Reviews. 2000 ; Vol. 100, No. 7. pp. 2479-2494.
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