Pausing on the Path to Robustness

Research output: Contribution to journalArticle

Abstract

Heat-shock proteins (Hsps) maintain homeostasis by assisting protein folding, and the transcriptional regulation of Hsp-coding genes has long been under study. Sawarkar et al. (2012) now report in Cell that Hsp90 is itself a transcriptional regulator required for RNA polymerase pausing, contributing to rapid, robust induction of many genes.

Original languageEnglish (US)
Pages (from-to)905-906
Number of pages2
JournalDevelopmental Cell
Volume22
Issue number5
DOIs
StatePublished - May 15 2012

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Genes
Protein folding
Protein Folding
DNA-Directed RNA Polymerases
Heat-Shock Proteins
Homeostasis

ASJC Scopus subject areas

  • Developmental Biology

Cite this

Pausing on the Path to Robustness. / Siegal, Mark; Rushlow, Christine.

In: Developmental Cell, Vol. 22, No. 5, 15.05.2012, p. 905-906.

Research output: Contribution to journalArticle

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