Patterns of molecular evolution among paralogous floral homeotic genes

Amy L. Lawton-Rauh, Edward S. Buckler IV, Michael D. Purugganan

Research output: Contribution to journalArticle

Abstract

The plant MADS-box regulatory gene family includes several loci that control different aspects of inflorescence and floral development. Orthologs to the Arabidopsis thaliana MADS-box floral meristem genes APETALA1 and CAULIFLOWER and the floral organ identity genes APETALA3 and PISTILLATA were isolated from the congeneric species Arabidopsis lyrata. Analysis of these loci between these two Arabidopsis species, as well as three other more distantly related taxa, reveal contrasting dynamics of molecular evolution between these paralogous floral regulatory genes. Among the four loci, the CAL locus evolves at a significantly faster rate, which may be associated with the evolution of genetic redundancy between CAL and AP1. Moreover, there are significant differences in the distribution of replacement and synonymous substitutions between the functional gene domains of different floral homeotic loci. These results indicate that divergence in developmental function among paralogous members of regulatory gene families is accompanied by changes in rate and pattern of sequence evolution among loci.

Original languageEnglish (US)
Pages (from-to)1037-1045
Number of pages9
JournalMolecular Biology and Evolution
Volume16
Issue number8
StatePublished - 1999

Fingerprint

homeotic genes
Molecular Evolution
Homeobox Genes
Regulator Genes
Arabidopsis
Genes
loci
gene
regulator genes
Inflorescence
Internal-External Control
Meristem
flowering
genes
molecular dynamics
meristems
Redundancy
substitution
Substitution reactions
Arabidopsis thaliana

Keywords

  • APETALA1
  • APETALA3
  • Arabidopsis lyrata
  • Arabidopsis thaliana
  • CAULIFLOWER
  • MADS- box
  • PISTILLATA

ASJC Scopus subject areas

  • Molecular Biology
  • Agricultural and Biological Sciences (miscellaneous)
  • Ecology, Evolution, Behavior and Systematics
  • Biochemistry, Genetics and Molecular Biology(all)
  • Genetics(clinical)
  • Biochemistry
  • Genetics

Cite this

Patterns of molecular evolution among paralogous floral homeotic genes. / Lawton-Rauh, Amy L.; Buckler IV, Edward S.; Purugganan, Michael D.

In: Molecular Biology and Evolution, Vol. 16, No. 8, 1999, p. 1037-1045.

Research output: Contribution to journalArticle

Lawton-Rauh, Amy L. ; Buckler IV, Edward S. ; Purugganan, Michael D. / Patterns of molecular evolution among paralogous floral homeotic genes. In: Molecular Biology and Evolution. 1999 ; Vol. 16, No. 8. pp. 1037-1045.
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