Pattern-Based Detection of Different Proteins Using an Array of Fluorescent Protein Surface Receptors

Laura Baldini, Andrew J. Wilson, Jason Hong, Andrew Hamilton

Research output: Contribution to journalArticle

Abstract

A small library of porphyrin derivatives whose fluorescence emission changes on binding to protein surfaces has been developed as a protein "fingerprinting" array. When incubated with different proteins, the array yields a characteristic response, specific for every protein analyte. At the same time, this design allows for the rapid screening of the porphyrin library for the identification of high affinity protein surface ligands.

Original languageEnglish (US)
Pages (from-to)5656-5657
Number of pages2
JournalJournal of the American Chemical Society
Volume126
Issue number18
DOIs
Publication statusPublished - May 12 2004

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ASJC Scopus subject areas

  • Chemistry(all)

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