Parallels between cerebellum- and amygdala-dependent conditioning

Javier F. Medina, J. Christopher Repa, Michael D. Mauk, Joseph Ledoux

Research output: Contribution to journalArticle

Abstract

Recent evidence from cerebellum-dependent motor learning and amygdala-dependent fear conditioning indicates that, despite being mediated by different brain systems, these forms of learning might use a similar sequence of events to form new memories. In each case, learning seems to induce changes in two different groups of neurons. Changes in the first class of cells are induced very rapidly during the initial stages of learning, whereas changes in the second class of cells develop more slowly and are resistant to extinction. So, anatomically distinct cell populations might contribute differentially to the initial encoding and the long-term storage of memory in these two systems.

Original languageEnglish (US)
Pages (from-to)122-131
Number of pages10
JournalNature Reviews Neuroscience
Volume3
Issue number2
DOIs
StatePublished - Feb 2002

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Amygdala
Cerebellum
Learning
Long-Term Memory
Fear
Neurons
Conditioning (Psychology)
Brain
Population

ASJC Scopus subject areas

  • Cell Biology
  • Neuroscience(all)

Cite this

Parallels between cerebellum- and amygdala-dependent conditioning. / Medina, Javier F.; Repa, J. Christopher; Mauk, Michael D.; Ledoux, Joseph.

In: Nature Reviews Neuroscience, Vol. 3, No. 2, 02.2002, p. 122-131.

Research output: Contribution to journalArticle

Medina, Javier F. ; Repa, J. Christopher ; Mauk, Michael D. ; Ledoux, Joseph. / Parallels between cerebellum- and amygdala-dependent conditioning. In: Nature Reviews Neuroscience. 2002 ; Vol. 3, No. 2. pp. 122-131.
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