Overview of HIV and AIDS. Biology and epidemiology of the virus

R. S. Klein, Marc Gourevitch

Research output: Contribution to journalReview article

Abstract

HIV-1 infects mononuclear cells using the CD4+ molecule and the chemical receptors of those cells. After a prolonged clinical latency period, the ability to replace destroyed cells is outpaced by ongoing cellular destruction, leading to the characteristic immunodeficiency of AIDS and its opportunistic infections and neoplasms. In the United States, the number of new cases of AIDS has diminished in recent years, although in some groups, such as women, the number of new cases continues to rise. In the developing world, AIDS remains a pandemic of huge proportions. In the absence of an effective vaccine, culturally appropriate efforts at education and behavior modification offer the best hope of controlling AIDS.

Original languageEnglish (US)
Pages (from-to)751-767
Number of pages17
JournalGastrointestinal Endoscopy Clinics of North America
Volume8
Issue number4
StatePublished - 1998

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Acquired Immunodeficiency Syndrome
Epidemiology
HIV
Viruses
Hope
CD4 Antigens
Aptitude
Behavior Therapy
Opportunistic Infections
Pandemics
HIV-1
Vaccines
Education
Neoplasms

ASJC Scopus subject areas

  • Gastroenterology
  • Surgery

Cite this

Overview of HIV and AIDS. Biology and epidemiology of the virus. / Klein, R. S.; Gourevitch, Marc.

In: Gastrointestinal Endoscopy Clinics of North America, Vol. 8, No. 4, 1998, p. 751-767.

Research output: Contribution to journalReview article

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