Oral contraceptive use may not preclude condom use: A study of non-pregnant African-American adolescent females

Richard A. Crosby, Ralph J. DiClemente, Gina M. Wingood, Laura F. Salazar, Eve Rose, Jessica M. Sales, Angela M. Caliendo

Research output: Contribution to journalArticle


Objective: To determine the association between oral contraceptive and condom use, and laboratory-confirmed sexually transmitted infection (STI) among African-American adolescent females at a high risk of STI acquisition. Methods: A cross-sectional study of 715 African-American adolescent females (15-21 years old) was conducted. Data collection included (a) an audio-computer-assisted self-interview and a self-collected vaginal swab for nucleic acid amplification testing of Trichomonas vaginalis, Chlamydia trachomatis and Neisseria gonorrhoeae. Results: The age-adjusted odds ratio (AOR) indicated a modest protective effect of oral contraceptive use against unprotected vaginal sex (UVS) using a 60-day recall period (AOR = 0.66; 95% CI 0.43 to 0.99). The age-adjusted difference in mean frequency of UVS in the past 60 days was non-significant (p = 0.23) as was condom use at last sex (p = 0.34). The age-AOR relative to STI prevalence also showed a protective effect (AOR = 0.60; 95% CI 0.36 to 0.98) for those using oral contraceptives. Conclusion: The findings suggest that the use of oral contraceptives may not preclude safer sex practices for the prevention of STIs among high-risk African-American adolescent females.

Original languageEnglish (US)
Pages (from-to)216-218
Number of pages3
JournalSexually transmitted infections
Issue number3
StatePublished - Jun 1 2007


ASJC Scopus subject areas

  • Dermatology
  • Infectious Diseases

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