Optical microcavities

Single virus detection and nanoparticle trapping

Frank Vollmer, Stephen Arnold

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Single polystyrene nanoparticles are detected from resonance wavelength fluctuations in toroidal and spherical microcavities. The magnitude of the wavelength-shift signal follows a reactive mechanism with inverse dependence on mode volume. By reducing the size of a microsphere cavity we demonstrate sensitivity to single Influenza A virions. Furthermore, we introduce a novel mechanism for trapping and accumulation of nanoparticles at the microcavity-sensorregion by utilizing light-force exerted in evanescent field gradients.

Original languageEnglish (US)
Title of host publicationBiosensing II
Volume7397
DOIs
StatePublished - 2009
EventBiosensing II - San Diego, CA, United States
Duration: Aug 4 2009Aug 6 2009

Other

OtherBiosensing II
CountryUnited States
CitySan Diego, CA
Period8/4/098/6/09

Fingerprint

Microcavity
Microcavities
viruses
Trapping
Viruses
Virus
Nanoparticles
trapping
Wavelength
Evanescent Field
Evanescent fields
influenza
nanoparticles
Microspheres
Influenza
Polystyrenes
wavelengths
polystyrene
Cavity
Fluctuations

Keywords

  • microcavity biosensor
  • optical nanoparticle trapping
  • optical resonance
  • virus detection

ASJC Scopus subject areas

  • Applied Mathematics
  • Computer Science Applications
  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

Cite this

Optical microcavities : Single virus detection and nanoparticle trapping. / Vollmer, Frank; Arnold, Stephen.

Biosensing II. Vol. 7397 2009. 739702.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Vollmer, F & Arnold, S 2009, Optical microcavities: Single virus detection and nanoparticle trapping. in Biosensing II. vol. 7397, 739702, Biosensing II, San Diego, CA, United States, 8/4/09. https://doi.org/10.1117/12.827264
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