Operation of a DNA robot arm inserted into a 2D DNA crystalline substrate

Baoquan Ding, Nadrian Seeman

Research output: Contribution to journalArticle

Abstract

The success of nanorobotics requires the precise placement and subsequent operation of specific nanomechanical devices at particular locations. The structural programmability of DNA makes it a particularly attractive system for nanorobotics. We have developed a cassette that enables the placement of a robust, sequence-dependent DNA robot arm within a two-dimensional (2D) crystalline DNA array. The cassette contains the device, an attachment site, and a reporter of state. We used atomic force microscopy to demonstrate that the rotary device is fully functional after insertion. Thus, a nanomechanical device can operate within a fixed frame of reference.

Original languageEnglish (US)
Pages (from-to)1583-1585
Number of pages3
JournalScience
Volume314
Issue number5805
DOIs
StatePublished - Dec 8 2006

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Equipment and Supplies
DNA
Atomic Force Microscopy
Oligonucleotide Array Sequence Analysis

ASJC Scopus subject areas

  • General

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Operation of a DNA robot arm inserted into a 2D DNA crystalline substrate. / Ding, Baoquan; Seeman, Nadrian.

In: Science, Vol. 314, No. 5805, 08.12.2006, p. 1583-1585.

Research output: Contribution to journalArticle

Ding, Baoquan ; Seeman, Nadrian. / Operation of a DNA robot arm inserted into a 2D DNA crystalline substrate. In: Science. 2006 ; Vol. 314, No. 5805. pp. 1583-1585.
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