Onset of cell proliferation in the shortened gut. Colonic hyperplasia after ileal resection

S. Nundy, Daniel Malamud, H. Obertop, J. Sczerban, R. A. Malt

Research output: Contribution to journalArticle

Abstract

Cytokinetics in colonic mucosa were studied after ileal resection in young female rats. The RNA content of the transverse colon was increased 32% after 7 days; after 14 days the increase was present throughout the colon. The DNA content of the ascending colon increased 29% after 10 days. Specific activity of DNA labeled with [ 3H-methyl]thymidine was elevated 29% in the ascending colon and elevated 49% in the descending colon on the 7th postoperative day. Colonic cell proliferation is stimulated within 1 week of ileal resection.

Original languageEnglish (US)
Pages (from-to)263-266
Number of pages4
JournalGastroenterology
Volume72
Issue number2
StatePublished - 1977

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Ascending Colon
Hyperplasia
Cell Proliferation
Descending Colon
Transverse Colon
DNA
Thymidine
Colon
Mucous Membrane
RNA

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Nundy, S., Malamud, D., Obertop, H., Sczerban, J., & Malt, R. A. (1977). Onset of cell proliferation in the shortened gut. Colonic hyperplasia after ileal resection. Gastroenterology, 72(2), 263-266.

Onset of cell proliferation in the shortened gut. Colonic hyperplasia after ileal resection. / Nundy, S.; Malamud, Daniel; Obertop, H.; Sczerban, J.; Malt, R. A.

In: Gastroenterology, Vol. 72, No. 2, 1977, p. 263-266.

Research output: Contribution to journalArticle

Nundy, S, Malamud, D, Obertop, H, Sczerban, J & Malt, RA 1977, 'Onset of cell proliferation in the shortened gut. Colonic hyperplasia after ileal resection', Gastroenterology, vol. 72, no. 2, pp. 263-266.
Nundy, S. ; Malamud, Daniel ; Obertop, H. ; Sczerban, J. ; Malt, R. A. / Onset of cell proliferation in the shortened gut. Colonic hyperplasia after ileal resection. In: Gastroenterology. 1977 ; Vol. 72, No. 2. pp. 263-266.
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