Objectifying eye movements during rapid number naming: Methodology for assessment of normative data for the King-Devick test

John Ross Rizzo, Todd E. Hudson, Weiwei Dai, Ninad Desai, Arash Yousefi, Dhaval Palsana, Ivan Selesnick, Laura J. Balcer, Steven L. Galetta, Janet C. Rucker

Research output: Contribution to journalArticle

Abstract

Objective Concussion is a major public health problem and considerable efforts are focused on sideline-based diagnostic testing to guide return-to-play decision-making and clinical care. The King-Devick (K-D) test, a sensitive sideline performance measure for concussion detection, reveals slowed reading times in acutely concussed subjects, as compared to healthy controls; however, the normal behavior of eye movements during the task and deficits underlying the slowing have not been defined. Methods Twelve healthy control subjects underwent quantitative eye tracking during digitized K-D testing. Results The total K-D reading time was 51.24 (± 9.7) seconds. A total of 145 saccades (± 15) per subject were generated, with average peak velocity 299.5°/s and average amplitude 8.2°. The average inter-saccadic interval was 248.4 ms. Task-specific horizontal and oblique saccades per subject numbered, respectively, 102 (± 10) and 17 (± 4). Subjects with the fewest saccades tended to blink more, resulting in a larger amount of missing data; whereas, subjects with the most saccades tended to make extra saccades during line transitions. Conclusions Establishment of normal and objective ocular motor behavior during the K-D test is a critical first step towards defining the range of deficits underlying abnormal testing in concussion. Further, it sets the groundwork for exploration of K-D correlations with cognitive dysfunction and saccadic paradigms that may reflect specific neuroanatomic deficits in the concussed brain.

Original languageEnglish (US)
Pages (from-to)232-239
Number of pages8
JournalJournal of the Neurological Sciences
Volume362
DOIs
StatePublished - Mar 15 2016

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Keywords

  • Brain concussion
  • Eye movement measurements
  • Eye movements
  • Saccades

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Objectifying eye movements during rapid number naming : Methodology for assessment of normative data for the King-Devick test. / Rizzo, John Ross; Hudson, Todd E.; Dai, Weiwei; Desai, Ninad; Yousefi, Arash; Palsana, Dhaval; Selesnick, Ivan; Balcer, Laura J.; Galetta, Steven L.; Rucker, Janet C.

In: Journal of the Neurological Sciences, Vol. 362, 15.03.2016, p. 232-239.

Research output: Contribution to journalArticle

Rizzo, John Ross ; Hudson, Todd E. ; Dai, Weiwei ; Desai, Ninad ; Yousefi, Arash ; Palsana, Dhaval ; Selesnick, Ivan ; Balcer, Laura J. ; Galetta, Steven L. ; Rucker, Janet C. / Objectifying eye movements during rapid number naming : Methodology for assessment of normative data for the King-Devick test. In: Journal of the Neurological Sciences. 2016 ; Vol. 362. pp. 232-239.
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abstract = "Objective Concussion is a major public health problem and considerable efforts are focused on sideline-based diagnostic testing to guide return-to-play decision-making and clinical care. The King-Devick (K-D) test, a sensitive sideline performance measure for concussion detection, reveals slowed reading times in acutely concussed subjects, as compared to healthy controls; however, the normal behavior of eye movements during the task and deficits underlying the slowing have not been defined. Methods Twelve healthy control subjects underwent quantitative eye tracking during digitized K-D testing. Results The total K-D reading time was 51.24 (± 9.7) seconds. A total of 145 saccades (± 15) per subject were generated, with average peak velocity 299.5°/s and average amplitude 8.2°. The average inter-saccadic interval was 248.4 ms. Task-specific horizontal and oblique saccades per subject numbered, respectively, 102 (± 10) and 17 (± 4). Subjects with the fewest saccades tended to blink more, resulting in a larger amount of missing data; whereas, subjects with the most saccades tended to make extra saccades during line transitions. Conclusions Establishment of normal and objective ocular motor behavior during the K-D test is a critical first step towards defining the range of deficits underlying abnormal testing in concussion. Further, it sets the groundwork for exploration of K-D correlations with cognitive dysfunction and saccadic paradigms that may reflect specific neuroanatomic deficits in the concussed brain.",
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AU - Yousefi, Arash

AU - Palsana, Dhaval

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