Nucleotide recognition by macrocyclic receptors

Andrew Hamilton, Alex Muehldorf, Suk Kyu Chang, Nalin Pant, Shyamaprosad Goswami, Donna van Engen

Research output: Contribution to journalArticle

Abstract

It is shown that complementary positioning of recognition sites (particularly hydrogen bonding, stacking and hydrophobic groups) into a macrocyclic structure can lead to very strong and specific complexation of uncharged organic molecules.

Original languageEnglish (US)
Pages (from-to)27-38
Number of pages12
JournalJournal of Inclusion Phenomena and Molecular Recognition in Chemistry
Volume7
Issue number1
DOIs
StatePublished - Feb 1989

Fingerprint

hydrogen bonding
nucleotides
Hydrogen Bonding
Complexation
positioning
Hydrogen bonds
Nucleotides
receptors
Molecules
hydrogen
molecules

Keywords

  • barbiturate
  • guanine
  • Molecular recognition
  • nucleotide
  • thymine

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Chemistry(all)

Cite this

Nucleotide recognition by macrocyclic receptors. / Hamilton, Andrew; Muehldorf, Alex; Chang, Suk Kyu; Pant, Nalin; Goswami, Shyamaprosad; van Engen, Donna.

In: Journal of Inclusion Phenomena and Molecular Recognition in Chemistry, Vol. 7, No. 1, 02.1989, p. 27-38.

Research output: Contribution to journalArticle

Hamilton, Andrew ; Muehldorf, Alex ; Chang, Suk Kyu ; Pant, Nalin ; Goswami, Shyamaprosad ; van Engen, Donna. / Nucleotide recognition by macrocyclic receptors. In: Journal of Inclusion Phenomena and Molecular Recognition in Chemistry. 1989 ; Vol. 7, No. 1. pp. 27-38.
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