Novel Nicotine Delivery Systems

P. S. Kumar, P. Clark, M. C. Brinkman, D. Saxena

Research output: Contribution to journalReview article

Abstract

Electronic nicotine delivery systems (ENDS) are devices that contain a power source, a heating element, and a tank or cartridge containing an "e-liquid," which is a mixture of nicotine and flavoring in a glycerol-propylene glycol vehicle. Their increasing popularity among adolescents might be attributed to aggressive marketing in physical venues, social media outlets, as well as irreversible changes caused by nicotine in the developing brains of youth and young adults, predisposing them to addictive behaviors. Adolescent ENDS users were 4 times more likely to initiate cigarette smoking, and the odds of quitting smoking were lower and, in many instances, delayed for those using ENDS. ENDS also renormalize cigarette-like behaviors, such as inhaling/exhaling smoke. The oral cavity is the initial point of contact of ENDS and the first affected system in humans. Oral health depends on an intricate balance in the interactions between oral bacteria and the human immune system, and dysbiosis of oral microbial communities underlies the etiology of periodontitis, caries, and oral cancer. Emerging evidence from subjects with periodontitis as well as periodontally healthy subjects demonstrates that e-cigarette use is associated with a compositional and functional shift in the oral microbiome, with an increase in opportunistic pathogens and virulence traits.

Original languageEnglish (US)
Pages (from-to)11-15
Number of pages5
JournalAdvances in dental research
Volume30
Issue number1
DOIs
StatePublished - Oct 1 2019

Fingerprint

Nicotine
Periodontitis
Tobacco Products
Smoking
Dysbiosis
Addictive Behavior
Social Media
Exhalation
Electric Power Supplies
Propylene Glycol
Mouth Neoplasms
Microbiota
Oral Health
Marketing
Smoke
Glycerol
Heating
Inhalation
Virulence
Mouth

Keywords

  • bacteria
  • DNA sequencing
  • electronic nicotine delivery systems
  • habituation
  • microbiology
  • tobacco products

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Novel Nicotine Delivery Systems. / Kumar, P. S.; Clark, P.; Brinkman, M. C.; Saxena, D.

In: Advances in dental research, Vol. 30, No. 1, 01.10.2019, p. 11-15.

Research output: Contribution to journalReview article

Kumar, P. S. ; Clark, P. ; Brinkman, M. C. ; Saxena, D. / Novel Nicotine Delivery Systems. In: Advances in dental research. 2019 ; Vol. 30, No. 1. pp. 11-15.
@article{41622d0f13ba47b48992a36ac03b102b,
title = "Novel Nicotine Delivery Systems",
abstract = "Electronic nicotine delivery systems (ENDS) are devices that contain a power source, a heating element, and a tank or cartridge containing an {"}e-liquid,{"} which is a mixture of nicotine and flavoring in a glycerol-propylene glycol vehicle. Their increasing popularity among adolescents might be attributed to aggressive marketing in physical venues, social media outlets, as well as irreversible changes caused by nicotine in the developing brains of youth and young adults, predisposing them to addictive behaviors. Adolescent ENDS users were 4 times more likely to initiate cigarette smoking, and the odds of quitting smoking were lower and, in many instances, delayed for those using ENDS. ENDS also renormalize cigarette-like behaviors, such as inhaling/exhaling smoke. The oral cavity is the initial point of contact of ENDS and the first affected system in humans. Oral health depends on an intricate balance in the interactions between oral bacteria and the human immune system, and dysbiosis of oral microbial communities underlies the etiology of periodontitis, caries, and oral cancer. Emerging evidence from subjects with periodontitis as well as periodontally healthy subjects demonstrates that e-cigarette use is associated with a compositional and functional shift in the oral microbiome, with an increase in opportunistic pathogens and virulence traits.",
keywords = "bacteria, DNA sequencing, electronic nicotine delivery systems, habituation, microbiology, tobacco products",
author = "Kumar, {P. S.} and P. Clark and Brinkman, {M. C.} and D. Saxena",
year = "2019",
month = "10",
day = "1",
doi = "10.1177/0022034519872475",
language = "English (US)",
volume = "30",
pages = "11--15",
journal = "Advances in dental research",
issn = "0895-9374",
publisher = "International Association for Dental Research",
number = "1",

}

TY - JOUR

T1 - Novel Nicotine Delivery Systems

AU - Kumar, P. S.

AU - Clark, P.

AU - Brinkman, M. C.

AU - Saxena, D.

PY - 2019/10/1

Y1 - 2019/10/1

N2 - Electronic nicotine delivery systems (ENDS) are devices that contain a power source, a heating element, and a tank or cartridge containing an "e-liquid," which is a mixture of nicotine and flavoring in a glycerol-propylene glycol vehicle. Their increasing popularity among adolescents might be attributed to aggressive marketing in physical venues, social media outlets, as well as irreversible changes caused by nicotine in the developing brains of youth and young adults, predisposing them to addictive behaviors. Adolescent ENDS users were 4 times more likely to initiate cigarette smoking, and the odds of quitting smoking were lower and, in many instances, delayed for those using ENDS. ENDS also renormalize cigarette-like behaviors, such as inhaling/exhaling smoke. The oral cavity is the initial point of contact of ENDS and the first affected system in humans. Oral health depends on an intricate balance in the interactions between oral bacteria and the human immune system, and dysbiosis of oral microbial communities underlies the etiology of periodontitis, caries, and oral cancer. Emerging evidence from subjects with periodontitis as well as periodontally healthy subjects demonstrates that e-cigarette use is associated with a compositional and functional shift in the oral microbiome, with an increase in opportunistic pathogens and virulence traits.

AB - Electronic nicotine delivery systems (ENDS) are devices that contain a power source, a heating element, and a tank or cartridge containing an "e-liquid," which is a mixture of nicotine and flavoring in a glycerol-propylene glycol vehicle. Their increasing popularity among adolescents might be attributed to aggressive marketing in physical venues, social media outlets, as well as irreversible changes caused by nicotine in the developing brains of youth and young adults, predisposing them to addictive behaviors. Adolescent ENDS users were 4 times more likely to initiate cigarette smoking, and the odds of quitting smoking were lower and, in many instances, delayed for those using ENDS. ENDS also renormalize cigarette-like behaviors, such as inhaling/exhaling smoke. The oral cavity is the initial point of contact of ENDS and the first affected system in humans. Oral health depends on an intricate balance in the interactions between oral bacteria and the human immune system, and dysbiosis of oral microbial communities underlies the etiology of periodontitis, caries, and oral cancer. Emerging evidence from subjects with periodontitis as well as periodontally healthy subjects demonstrates that e-cigarette use is associated with a compositional and functional shift in the oral microbiome, with an increase in opportunistic pathogens and virulence traits.

KW - bacteria

KW - DNA sequencing

KW - electronic nicotine delivery systems

KW - habituation

KW - microbiology

KW - tobacco products

UR - http://www.scopus.com/inward/record.url?scp=85072393297&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85072393297&partnerID=8YFLogxK

U2 - 10.1177/0022034519872475

DO - 10.1177/0022034519872475

M3 - Review article

C2 - 31538804

AN - SCOPUS:85072393297

VL - 30

SP - 11

EP - 15

JO - Advances in dental research

JF - Advances in dental research

SN - 0895-9374

IS - 1

ER -