"Nought May Endure but Mutability": Spliceosome Dynamics and the Regulation of Splicing

Duncan Smith, Charles C. Query, Maria M. Konarska

Research output: Contribution to journalArticle

Abstract

The spliceosome is both compositionally and conformationally dynamic. Each transition along the splicing pathway presents an opportunity for progression, pausing, or discard, allowing splice site choice to be regulated throughout both the assembly and catalytic phases of the reaction.

Original languageEnglish (US)
Pages (from-to)657-666
Number of pages10
JournalMolecular Cell
Volume30
Issue number6
DOIs
StatePublished - Jun 20 2008

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Spliceosomes

ASJC Scopus subject areas

  • Molecular Biology

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"Nought May Endure but Mutability" : Spliceosome Dynamics and the Regulation of Splicing. / Smith, Duncan; Query, Charles C.; Konarska, Maria M.

In: Molecular Cell, Vol. 30, No. 6, 20.06.2008, p. 657-666.

Research output: Contribution to journalArticle

Smith, Duncan ; Query, Charles C. ; Konarska, Maria M. / "Nought May Endure but Mutability" : Spliceosome Dynamics and the Regulation of Splicing. In: Molecular Cell. 2008 ; Vol. 30, No. 6. pp. 657-666.
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