New perspectives on the mechanisms for orientation selectivity

Haim Sompolinsky, Robert Shapley

Research output: Contribution to journalArticle

Abstract

Since the discovery of orientation selectivity by Hubel and Wiesel, the mechanisms responsible for this remarkable operation in the visual cortex have been controversial. Experimental studies over the past year have highlighted the contribution of feedforward thalamo-cortical afferents, as proposed originally by Hubel and Wiesel, but they have also indicated that this contribution alone is insufficient to account for the sharp orientation tuning observed in the visual cortex. Recent advances in understanding the functional architecture of local cortical circuitry have led to new proposals for the involvement of intracortical recurrent excitation and inhibition in orientation selectivity. Establishing how these two mechanisms work together remains an important experimental and theoretical challenge.

Original languageEnglish (US)
Pages (from-to)514-522
Number of pages9
JournalCurrent Opinion in Neurobiology
Volume7
Issue number4
DOIs
StatePublished - Aug 1997

Fingerprint

Visual Cortex

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

New perspectives on the mechanisms for orientation selectivity. / Sompolinsky, Haim; Shapley, Robert.

In: Current Opinion in Neurobiology, Vol. 7, No. 4, 08.1997, p. 514-522.

Research output: Contribution to journalArticle

@article{1a23b2a6bdd344ccbe5da6c45e938da8,
title = "New perspectives on the mechanisms for orientation selectivity",
abstract = "Since the discovery of orientation selectivity by Hubel and Wiesel, the mechanisms responsible for this remarkable operation in the visual cortex have been controversial. Experimental studies over the past year have highlighted the contribution of feedforward thalamo-cortical afferents, as proposed originally by Hubel and Wiesel, but they have also indicated that this contribution alone is insufficient to account for the sharp orientation tuning observed in the visual cortex. Recent advances in understanding the functional architecture of local cortical circuitry have led to new proposals for the involvement of intracortical recurrent excitation and inhibition in orientation selectivity. Establishing how these two mechanisms work together remains an important experimental and theoretical challenge.",
author = "Haim Sompolinsky and Robert Shapley",
year = "1997",
month = "8",
doi = "10.1016/S0959-4388(97)80031-1",
language = "English (US)",
volume = "7",
pages = "514--522",
journal = "Current Opinion in Neurobiology",
issn = "0959-4388",
publisher = "Elsevier Limited",
number = "4",

}

TY - JOUR

T1 - New perspectives on the mechanisms for orientation selectivity

AU - Sompolinsky, Haim

AU - Shapley, Robert

PY - 1997/8

Y1 - 1997/8

N2 - Since the discovery of orientation selectivity by Hubel and Wiesel, the mechanisms responsible for this remarkable operation in the visual cortex have been controversial. Experimental studies over the past year have highlighted the contribution of feedforward thalamo-cortical afferents, as proposed originally by Hubel and Wiesel, but they have also indicated that this contribution alone is insufficient to account for the sharp orientation tuning observed in the visual cortex. Recent advances in understanding the functional architecture of local cortical circuitry have led to new proposals for the involvement of intracortical recurrent excitation and inhibition in orientation selectivity. Establishing how these two mechanisms work together remains an important experimental and theoretical challenge.

AB - Since the discovery of orientation selectivity by Hubel and Wiesel, the mechanisms responsible for this remarkable operation in the visual cortex have been controversial. Experimental studies over the past year have highlighted the contribution of feedforward thalamo-cortical afferents, as proposed originally by Hubel and Wiesel, but they have also indicated that this contribution alone is insufficient to account for the sharp orientation tuning observed in the visual cortex. Recent advances in understanding the functional architecture of local cortical circuitry have led to new proposals for the involvement of intracortical recurrent excitation and inhibition in orientation selectivity. Establishing how these two mechanisms work together remains an important experimental and theoretical challenge.

UR - http://www.scopus.com/inward/record.url?scp=0031417362&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031417362&partnerID=8YFLogxK

U2 - 10.1016/S0959-4388(97)80031-1

DO - 10.1016/S0959-4388(97)80031-1

M3 - Article

C2 - 9287203

AN - SCOPUS:0031417362

VL - 7

SP - 514

EP - 522

JO - Current Opinion in Neurobiology

JF - Current Opinion in Neurobiology

SN - 0959-4388

IS - 4

ER -