New approaches to genomic analysis using single molecules

D. C. Schwartz, T. Anantharaman, C. Aston, Bhubaneswar Mishra, V. Clarke, D. Gebauer, S. Delobette, E. Dimalanta, J. Edington, A. Evenzehav, J. Giacalone, C. Hiort, E. Huff, J. Jing, Z. Lail

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Despite the rapid progress in the human genome project effort, there is little doubt that radically new conceptual approaches are needed before routine whole genome-based analyses can be undertaken by both basic research and clinical laboratories. Physical mapping of genomes, using restriction endonucleases, has played a major role in the identification and characterization of various loci. Optical mapping is the first practical non-electrophoretic genomic mapping approach. It is a single molecule methodology for the rapid production of ordered restriction maps from single DNA molecules.

Original languageEnglish (US)
Title of host publicationProceedings of the Annual International Conference on Computational Molecular Biology, RECOMB
Editors Anon
PublisherACM
Pages248-250
Number of pages3
StatePublished - 1998
EventProceedings of the 1998 2nd Annual International Conference on Computational Molecular Biology - New York, NY, USA
Duration: Mar 22 1998Mar 25 1998

Other

OtherProceedings of the 1998 2nd Annual International Conference on Computational Molecular Biology
CityNew York, NY, USA
Period3/22/983/25/98

Fingerprint

Human Genome Project
Chromosome Mapping
DNA Restriction Enzymes
Genes
Genome
Molecules
DNA
Research
Clinical laboratories
Research laboratories

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Computer Science(all)

Cite this

Schwartz, D. C., Anantharaman, T., Aston, C., Mishra, B., Clarke, V., Gebauer, D., ... Lail, Z. (1998). New approaches to genomic analysis using single molecules. In Anon (Ed.), Proceedings of the Annual International Conference on Computational Molecular Biology, RECOMB (pp. 248-250). ACM.

New approaches to genomic analysis using single molecules. / Schwartz, D. C.; Anantharaman, T.; Aston, C.; Mishra, Bhubaneswar; Clarke, V.; Gebauer, D.; Delobette, S.; Dimalanta, E.; Edington, J.; Evenzehav, A.; Giacalone, J.; Hiort, C.; Huff, E.; Jing, J.; Lail, Z.

Proceedings of the Annual International Conference on Computational Molecular Biology, RECOMB. ed. / Anon. ACM, 1998. p. 248-250.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Schwartz, DC, Anantharaman, T, Aston, C, Mishra, B, Clarke, V, Gebauer, D, Delobette, S, Dimalanta, E, Edington, J, Evenzehav, A, Giacalone, J, Hiort, C, Huff, E, Jing, J & Lail, Z 1998, New approaches to genomic analysis using single molecules. in Anon (ed.), Proceedings of the Annual International Conference on Computational Molecular Biology, RECOMB. ACM, pp. 248-250, Proceedings of the 1998 2nd Annual International Conference on Computational Molecular Biology, New York, NY, USA, 3/22/98.
Schwartz DC, Anantharaman T, Aston C, Mishra B, Clarke V, Gebauer D et al. New approaches to genomic analysis using single molecules. In Anon, editor, Proceedings of the Annual International Conference on Computational Molecular Biology, RECOMB. ACM. 1998. p. 248-250
Schwartz, D. C. ; Anantharaman, T. ; Aston, C. ; Mishra, Bhubaneswar ; Clarke, V. ; Gebauer, D. ; Delobette, S. ; Dimalanta, E. ; Edington, J. ; Evenzehav, A. ; Giacalone, J. ; Hiort, C. ; Huff, E. ; Jing, J. ; Lail, Z. / New approaches to genomic analysis using single molecules. Proceedings of the Annual International Conference on Computational Molecular Biology, RECOMB. editor / Anon. ACM, 1998. pp. 248-250
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