Neuronal adaptation to visual motion in area MT of the macaque

Research output: Contribution to journalArticle

Abstract

The responsivity of primary sensory cortical neurons is reduced following prolonged adaptation, but such adaptation has been little studied in higher sensory areas. Adaptation to visual motion has strong perceptual effects, so we studied the effect of prolonged stimulation on neuronal responsivity in the macaque's area MT, a cortical area whose importance to visual motion perception is well established. We adapted MT neurons with sinusoidal gratings drifting in the preferred or null direction. Preferred adaptation reduced the responsiveness of MT cells, primarily by changing their contrast gain, and this effect was spatially specific within the receptive field. Null adaptation reduced the ability of null gratings to inhibit the response to a simultaneously presented preferred stimulus. While both preferred and null adaptation alter MT responses, these effects probably do not occur in MT neurons but are likely to reflect adaptation-induced changes in contrast gain earlier in the visual pathway.

Original languageEnglish (US)
Pages (from-to)681-691
Number of pages11
JournalNeuron
Volume39
Issue number4
DOIs
StatePublished - Aug 14 2003

Fingerprint

Macaca
Motion Perception
Neurons
Visual Perception
Aptitude
Visual Pathways
Sensory Receptor Cells
Direction compound

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Neuronal adaptation to visual motion in area MT of the macaque. / Kohn, Adam; Movshon, J. Anthony.

In: Neuron, Vol. 39, No. 4, 14.08.2003, p. 681-691.

Research output: Contribution to journalArticle

@article{583894b2d9e0408e91ef8b437bcc311d,
title = "Neuronal adaptation to visual motion in area MT of the macaque",
abstract = "The responsivity of primary sensory cortical neurons is reduced following prolonged adaptation, but such adaptation has been little studied in higher sensory areas. Adaptation to visual motion has strong perceptual effects, so we studied the effect of prolonged stimulation on neuronal responsivity in the macaque's area MT, a cortical area whose importance to visual motion perception is well established. We adapted MT neurons with sinusoidal gratings drifting in the preferred or null direction. Preferred adaptation reduced the responsiveness of MT cells, primarily by changing their contrast gain, and this effect was spatially specific within the receptive field. Null adaptation reduced the ability of null gratings to inhibit the response to a simultaneously presented preferred stimulus. While both preferred and null adaptation alter MT responses, these effects probably do not occur in MT neurons but are likely to reflect adaptation-induced changes in contrast gain earlier in the visual pathway.",
author = "Adam Kohn and Movshon, {J. Anthony}",
year = "2003",
month = "8",
day = "14",
doi = "10.1016/S0896-6273(03)00438-0",
language = "English (US)",
volume = "39",
pages = "681--691",
journal = "Neuron",
issn = "0896-6273",
publisher = "Cell Press",
number = "4",

}

TY - JOUR

T1 - Neuronal adaptation to visual motion in area MT of the macaque

AU - Kohn, Adam

AU - Movshon, J. Anthony

PY - 2003/8/14

Y1 - 2003/8/14

N2 - The responsivity of primary sensory cortical neurons is reduced following prolonged adaptation, but such adaptation has been little studied in higher sensory areas. Adaptation to visual motion has strong perceptual effects, so we studied the effect of prolonged stimulation on neuronal responsivity in the macaque's area MT, a cortical area whose importance to visual motion perception is well established. We adapted MT neurons with sinusoidal gratings drifting in the preferred or null direction. Preferred adaptation reduced the responsiveness of MT cells, primarily by changing their contrast gain, and this effect was spatially specific within the receptive field. Null adaptation reduced the ability of null gratings to inhibit the response to a simultaneously presented preferred stimulus. While both preferred and null adaptation alter MT responses, these effects probably do not occur in MT neurons but are likely to reflect adaptation-induced changes in contrast gain earlier in the visual pathway.

AB - The responsivity of primary sensory cortical neurons is reduced following prolonged adaptation, but such adaptation has been little studied in higher sensory areas. Adaptation to visual motion has strong perceptual effects, so we studied the effect of prolonged stimulation on neuronal responsivity in the macaque's area MT, a cortical area whose importance to visual motion perception is well established. We adapted MT neurons with sinusoidal gratings drifting in the preferred or null direction. Preferred adaptation reduced the responsiveness of MT cells, primarily by changing their contrast gain, and this effect was spatially specific within the receptive field. Null adaptation reduced the ability of null gratings to inhibit the response to a simultaneously presented preferred stimulus. While both preferred and null adaptation alter MT responses, these effects probably do not occur in MT neurons but are likely to reflect adaptation-induced changes in contrast gain earlier in the visual pathway.

UR - http://www.scopus.com/inward/record.url?scp=0043022292&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0043022292&partnerID=8YFLogxK

U2 - 10.1016/S0896-6273(03)00438-0

DO - 10.1016/S0896-6273(03)00438-0

M3 - Article

VL - 39

SP - 681

EP - 691

JO - Neuron

JF - Neuron

SN - 0896-6273

IS - 4

ER -