MutaGeneSys: Estimating individual disease susceptibility based on genome-wide SNP array data

Julia Stoyanovich, Itsik Pe'er

    Research output: Contribution to journalArticle

    Abstract

    Summary: We present MutaGeneSys: a system that uses genome-wide genotype data to estimate disease susceptibility. Our system integrates three data sources: the International HapMap project, whole-genome marker correlation data and the Online Mendelian Inheritance in Man (OMIM) database. It accepts SNP data of individuals as query input and delivers disease susceptibility hypotheses even if the original set of typed SNPs is incomplete. Our system is scalable and flexible: it produces population, technology and confidence-specific predictions in interactive time.

    Original languageEnglish (US)
    Pages (from-to)440-442
    Number of pages3
    JournalBioinformatics
    Volume24
    Issue number3
    DOIs
    StatePublished - Feb 1 2008

    Fingerprint

    Disease Susceptibility
    Susceptibility
    Single Nucleotide Polymorphism
    Genome
    Genes
    HapMap Project
    Genetic Databases
    Information Storage and Retrieval
    Genotype
    Databases
    Technology
    Population
    Confidence
    Integrate
    Query
    Prediction
    Estimate

    ASJC Scopus subject areas

    • Clinical Biochemistry
    • Computational Theory and Mathematics
    • Computer Science Applications

    Cite this

    MutaGeneSys : Estimating individual disease susceptibility based on genome-wide SNP array data. / Stoyanovich, Julia; Pe'er, Itsik.

    In: Bioinformatics, Vol. 24, No. 3, 01.02.2008, p. 440-442.

    Research output: Contribution to journalArticle

    Stoyanovich, Julia ; Pe'er, Itsik. / MutaGeneSys : Estimating individual disease susceptibility based on genome-wide SNP array data. In: Bioinformatics. 2008 ; Vol. 24, No. 3. pp. 440-442.
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