Multi-species integrative biclustering

Peter Waltman, Thadeous Kacmarczyk, Ashley R. Bate, Daniel B. Kearns, David J. Reiss, Patrick Eichenberger, Richard Bonneau

Research output: Contribution to journalArticle

Abstract

We describe an algorithm, multi-species cMonkey, for the simultaneous biclustering of heterogeneous multiple-species data collections and apply the algorithm to a group of bacteria containing Bacillus subtilis, Bacillus anthracis, and Listeria monocytogenes. The algorithm reveals evolutionary insights into the surprisingly high degree of conservation of regulatory modules across these three species and allows data and insights from well-studied organisms to complement the analysis of related but less well studied organisms.

Original languageEnglish (US)
JournalGenome Biology
DOIs
StateAccepted/In press - Sep 29 2010

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Bacillus anthracis
organisms
Listeria monocytogenes
Bacillus subtilis
complement
Bacteria
bacterium
bacteria
organism
analysis

ASJC Scopus subject areas

  • Genetics
  • Cell Biology
  • Ecology, Evolution, Behavior and Systematics

Cite this

Waltman, P., Kacmarczyk, T., Bate, A. R., Kearns, D. B., Reiss, D. J., Eichenberger, P., & Bonneau, R. (Accepted/In press). Multi-species integrative biclustering. Genome Biology. https://doi.org/10.1186/gb-2010-11-9-r96

Multi-species integrative biclustering. / Waltman, Peter; Kacmarczyk, Thadeous; Bate, Ashley R.; Kearns, Daniel B.; Reiss, David J.; Eichenberger, Patrick; Bonneau, Richard.

In: Genome Biology, 29.09.2010.

Research output: Contribution to journalArticle

Waltman P, Kacmarczyk T, Bate AR, Kearns DB, Reiss DJ, Eichenberger P et al. Multi-species integrative biclustering. Genome Biology. 2010 Sep 29. https://doi.org/10.1186/gb-2010-11-9-r96
Waltman, Peter ; Kacmarczyk, Thadeous ; Bate, Ashley R. ; Kearns, Daniel B. ; Reiss, David J. ; Eichenberger, Patrick ; Bonneau, Richard. / Multi-species integrative biclustering. In: Genome Biology. 2010.
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