Mouthwash use and dentures in relation to oral epithelial dysplasia

D. E. Morse, Ralph Katz, D. G. Pendrys, T. R. Holford, D. J. Krutchkoff, E. Eisenberg, D. L. Kosis, S. Kerpel, P. Freedman, S. T. Mayne

Research output: Contribution to journalArticle

Abstract

This case-control study investigated the potential association between oral epithelial dysplasia (OED) and both mouthwash and denture use. Incident OED cases aged 20-79 years were identified through two oral pathology laboratories. Controls were pair-matched (1:1) to cases on age (± 5 years), gender, appointment date and surgeon. A telephone interview was used to obtain exposure information. Odds ratios (ORs) and 95% confidence intervals (95% CIs) were generated using conditional logistic regression. Based upon 127 case-control pairs and after adjusting for smoking, drinking, education and either denture or mouthwash use, the OR for OED and regular mouthwash use (1+ uses/week for 6+ months) was 0.8 (95% CI, 0.4-1.5) while the OR for OED and wearing a denture was 0.7 (95% CI, 0.4-1.3). There were no clear trends of increased OED risk with increased mouthwash use or years of denture wearing. Our findings suggest that neither mouthwash nor denture use are associated positively with OED risk.

Original languageEnglish (US)
Pages (from-to)338-343
Number of pages6
JournalOral Oncology
Volume33
Issue number5
DOIs
StatePublished - Sep 1997

Fingerprint

Mouthwashes
Dentures
Odds Ratio
Confidence Intervals
Oral Pathology
Drinking
Case-Control Studies
Appointments and Schedules
Logistic Models
Smoking
Interviews
Education

Keywords

  • Dentures
  • Dysplasia
  • Epidemiology
  • Mouth neoplasms
  • Mouthwashes
  • Precancerous conditions
  • Risk factors

ASJC Scopus subject areas

  • Oncology

Cite this

Morse, D. E., Katz, R., Pendrys, D. G., Holford, T. R., Krutchkoff, D. J., Eisenberg, E., ... Mayne, S. T. (1997). Mouthwash use and dentures in relation to oral epithelial dysplasia. Oral Oncology, 33(5), 338-343. https://doi.org/10.1016/S1368-8375(97)00019-5

Mouthwash use and dentures in relation to oral epithelial dysplasia. / Morse, D. E.; Katz, Ralph; Pendrys, D. G.; Holford, T. R.; Krutchkoff, D. J.; Eisenberg, E.; Kosis, D. L.; Kerpel, S.; Freedman, P.; Mayne, S. T.

In: Oral Oncology, Vol. 33, No. 5, 09.1997, p. 338-343.

Research output: Contribution to journalArticle

Morse, DE, Katz, R, Pendrys, DG, Holford, TR, Krutchkoff, DJ, Eisenberg, E, Kosis, DL, Kerpel, S, Freedman, P & Mayne, ST 1997, 'Mouthwash use and dentures in relation to oral epithelial dysplasia', Oral Oncology, vol. 33, no. 5, pp. 338-343. https://doi.org/10.1016/S1368-8375(97)00019-5
Morse DE, Katz R, Pendrys DG, Holford TR, Krutchkoff DJ, Eisenberg E et al. Mouthwash use and dentures in relation to oral epithelial dysplasia. Oral Oncology. 1997 Sep;33(5):338-343. https://doi.org/10.1016/S1368-8375(97)00019-5
Morse, D. E. ; Katz, Ralph ; Pendrys, D. G. ; Holford, T. R. ; Krutchkoff, D. J. ; Eisenberg, E. ; Kosis, D. L. ; Kerpel, S. ; Freedman, P. ; Mayne, S. T. / Mouthwash use and dentures in relation to oral epithelial dysplasia. In: Oral Oncology. 1997 ; Vol. 33, No. 5. pp. 338-343.
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