Monofunctionalization of dendrimers with use of microwave-assisted 1,3-dipolar cycloadditions

Yoon Kunsang, Poorva Goyal, Marcus Weck

Research output: Contribution to journalArticle

Abstract

Monofunctionalized polyamide-based dendrimers containing either a terminal azide or alkyne moiety have been designed and synthesized via a convergent synthetic approach. The monofunctionalization allows for the single attachment of a functional moiety in quantitative yields by using 1,3-dipolar cycloadditions, thereby opening the possibility for targeted dendrimer functionalization.

Original languageEnglish (US)
Pages (from-to)2051-2054
Number of pages4
JournalOrganic Letters
Volume9
Issue number11
DOIs
StatePublished - May 24 2007

Fingerprint

Dendrimers
Cycloaddition
dendrimers
Cycloaddition Reaction
cycloaddition
Microwaves
microwaves
Alkynes
Azides
Nylons
alkynes
attachment

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Monofunctionalization of dendrimers with use of microwave-assisted 1,3-dipolar cycloadditions. / Kunsang, Yoon; Goyal, Poorva; Weck, Marcus.

In: Organic Letters, Vol. 9, No. 11, 24.05.2007, p. 2051-2054.

Research output: Contribution to journalArticle

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