Acceleration of the 1,4-addition of a thiol to a maleimide can be achieved by binding the electrophile into a synthetic receptor containing hydrogen bonding sites that can interact with the carbonyl group and so stabilize the developing oxyanion in the transition state.
|Original language||English (US)|
|Number of pages||5|
|Journal||New Journal of Chemistry|
|State||Published - Jan 1 1997|
ASJC Scopus subject areas
- Materials Chemistry