Molecular recognition and catalysis

Incorporation of an "oxyanion hole" into a synthetic receptor

Erkang Fan, Cristina Vicent, Andrew Hamilton

Research output: Contribution to journalArticle

Abstract

Acceleration of the 1,4-addition of a thiol to a maleimide can be achieved by binding the electrophile into a synthetic receptor containing hydrogen bonding sites that can interact with the carbonyl group and so stabilize the developing oxyanion in the transition state.

Original languageEnglish (US)
Pages (from-to)81-85
Number of pages5
JournalNew Journal of Chemistry
Volume21
Issue number1
StatePublished - 1997

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Artificial Receptors
Molecular recognition
Sulfhydryl Compounds
Catalysis
Hydrogen bonds
maleimide

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Molecular recognition and catalysis : Incorporation of an "oxyanion hole" into a synthetic receptor. / Fan, Erkang; Vicent, Cristina; Hamilton, Andrew.

In: New Journal of Chemistry, Vol. 21, No. 1, 1997, p. 81-85.

Research output: Contribution to journalArticle

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