Molecular evidence on the origin and evolution of glutinous rice

Kenneth M. Olsen, Michael D. Purugganan

Research output: Contribution to journalArticle

Abstract

Glutinous rice is a major type of cultivated rice with long-standing cultural importance in Asia. A mutation in an intron 1 splice donor site of the Waxy gene is responsible for the change in endosperm starch leading to the glutinous phenotype. Here we examine an allele genealogy of the Waxy locus to trace the evolutionary and geographical origins of this phenotype. On the basis of 105 glutinous and nonglutinous landraces from across Asia, we find evidence that the splice donor mutation has a single evolutionary origin and that it probably arose in Southeast Asia. Nucleotide diversity measures indicate that the origin of glutinous rice is associated with reduced genetic variation characteristic of selection at the Waxy locus; comparison with an unlinked locus, RGRC2, confirms that this pattern is specific to Waxy. In addition, we find that many nonglutinous varieties in Northeast Asia also carry the splice donor site mutation, suggesting that partial suppression of this mutation may have played an important role in the development of Northeast Asian nonglutinous rice. This study demonstrates the utility of phylogeographic approaches for understanding trait diversification in crops, and it contributes to growing evidence on the importance of modifier loci in the evolution of domestication traits.

Original languageEnglish (US)
Pages (from-to)941-950
Number of pages10
JournalGenetics
Volume162
Issue number2
StatePublished - Oct 1 2002

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RNA Splice Sites
Mutation
Genealogy and Heraldry
Phenotype
Southeastern Asia
Endosperm
Starch
Introns
Nucleotides
Alleles
Oryza
Genes
Domestication

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

Cite this

Molecular evidence on the origin and evolution of glutinous rice. / Olsen, Kenneth M.; Purugganan, Michael D.

In: Genetics, Vol. 162, No. 2, 01.10.2002, p. 941-950.

Research output: Contribution to journalArticle

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