MiRò: A miRNA knowledge base

A. Laganà, S. Forte, A. Giudice, M. R. Arena, P. L. Puglisi, R. Giugno, A. Pulvirenti, Dennis Shasha, A. Ferro

Research output: Contribution to journalArticle

Abstract

miRò is a web-based knowledge base that provides users with miRNA-phenotype associations in humans. It integrates data from various online sources, such as databases of miRNAs, ontologies, diseases and targets, into a unified database equipped with an intuitive and flexible query interface and data mining facilities. The main goal of miRò is the establishment of a knowledge base which allows non-trivial analysis through sophisticated mining techniques and the introduction of a new layer of associations between genes and phenotypes inferred based on miRNAs annotations. Furthermore, a specificity function applied to validated data highlights the most significant associations. The miRò web site is available at: http://ferrolab.dmi.unict.it/miro.

Original languageEnglish (US)
Article numberbap008
JournalDatabase
Volume2009
DOIs
StatePublished - 2014

Fingerprint

Knowledge Bases
MicroRNAs
microRNA
phenotype
Databases
Data mining
Phenotype
Ontology
Websites
Data Mining
Genes
genes
methodology

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Information Systems

Cite this

Laganà, A., Forte, S., Giudice, A., Arena, M. R., Puglisi, P. L., Giugno, R., ... Ferro, A. (2014). MiRò: A miRNA knowledge base. Database, 2009, [bap008]. https://doi.org/10.1093/database/bap008

MiRò : A miRNA knowledge base. / Laganà, A.; Forte, S.; Giudice, A.; Arena, M. R.; Puglisi, P. L.; Giugno, R.; Pulvirenti, A.; Shasha, Dennis; Ferro, A.

In: Database, Vol. 2009, bap008, 2014.

Research output: Contribution to journalArticle

Laganà, A, Forte, S, Giudice, A, Arena, MR, Puglisi, PL, Giugno, R, Pulvirenti, A, Shasha, D & Ferro, A 2014, 'MiRò: A miRNA knowledge base', Database, vol. 2009, bap008. https://doi.org/10.1093/database/bap008
Laganà A, Forte S, Giudice A, Arena MR, Puglisi PL, Giugno R et al. MiRò: A miRNA knowledge base. Database. 2014;2009. bap008. https://doi.org/10.1093/database/bap008
Laganà, A. ; Forte, S. ; Giudice, A. ; Arena, M. R. ; Puglisi, P. L. ; Giugno, R. ; Pulvirenti, A. ; Shasha, Dennis ; Ferro, A. / MiRò : A miRNA knowledge base. In: Database. 2014 ; Vol. 2009.
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