Microstimulation of inferotemporal cortex influences face categorization

Seyed Reza Afraz, Roozbeh Kiani, Hossein Esteky

Research output: Contribution to journalArticle

Abstract

The inferior temporal cortex (IT) of primates is thought to be the final visual area in the ventral stream of cortical areas responsible for object recognition. Consistent with this hypothesis, single IT neurons respond selectively to highly complex visual stimuli such as faces. However, a direct causal link between the activity of face-selective neurons and face perception has not been demonstrated. In the present study of macaque monkeys, we artificially activated small clusters of IT neurons by means of electrical microstimulation while the monkeys performed a categorization task, judging whether noisy visual images belonged to 'face' or 'non-face' categories. Here we show that microstimulation of face-selective sites, but not other sites, strongly biased the monkeys' decisions towards the face category. The magnitude of the effect depended upon the degree of face selectivity of the stimulation site, the size of the stimulated cluster of face-selective neurons, and the exact timing of microstimulation. Our results establish a causal relationship between the activity of face-selective neurons and face perception.

Original languageEnglish (US)
Pages (from-to)692-695
Number of pages4
JournalNature
Volume442
Issue number7103
DOIs
StatePublished - Aug 10 2006

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Neurons
Temporal Lobe
Haplorhini
Macaca
Primates
Facial Recognition

ASJC Scopus subject areas

  • General

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Microstimulation of inferotemporal cortex influences face categorization. / Afraz, Seyed Reza; Kiani, Roozbeh; Esteky, Hossein.

In: Nature, Vol. 442, No. 7103, 10.08.2006, p. 692-695.

Research output: Contribution to journalArticle

Afraz, Seyed Reza ; Kiani, Roozbeh ; Esteky, Hossein. / Microstimulation of inferotemporal cortex influences face categorization. In: Nature. 2006 ; Vol. 442, No. 7103. pp. 692-695.
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