MicroParticle photophysics illuminates viral bio-sensing

S. Arnold, R. Ramjit, D. Keng, V. Kolchenko, I. Teraoka

Research output: Contribution to journalArticle

Abstract

The authors present an approach for specific and rapid unlabeled detection of a virus by using a microsphere-based whispering gallery mode sensor that transduces the interaction of a whole virus with an anchored antibody. They show theoretically that this sensor can detect a single virion below the mass of HIV. A micro-fluidic device is presented that enables the discrimination between viruses of similar size and shape.

Original languageEnglish (US)
Pages (from-to)65-83
Number of pages19
JournalFaraday discussions
Volume137
DOIs
StatePublished - Jan 1 2007

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry

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