Microfabricated nerve-electrode interfaces in neural prosthetics and neural engineering

Rafael Song, Ahmed M.S. Ibrahim, Amr N. Rabie, Jongyoon Han, Samuel J. Lin

    Research output: Contribution to journalArticle

    Abstract

    Neural interfaces and implants are finding more clinical applications and there are rapid technological advances for more efficient and safe design, fabrication and materials to establish high-fidelity neural interfaces. In this review paper, we highlight new developments of the microfabricated electrodes and substrates with regard to the design, materials, fabrication and their clinical applications. There is a noticeable trend towards integration of microfluidic modules on a single neural platform. In addition to the microelectrodes for neural recording and stimulation, microfluidic channels are integrated into a nerve-electrode interface to explore the rich neurochemistry present at the neural interface and exploit it for enhanced electrochemical stimulation and recording of the central and peripheral nervous system.

    Original languageEnglish (US)
    Pages (from-to)113-134
    Number of pages22
    JournalBiotechnology and Genetic Engineering Reviews
    Volume29
    Issue number2
    DOIs
    StatePublished - Oct 1 2013

    Fingerprint

    Microfluidics
    Prosthetics
    Electrodes
    Neurochemistry
    Fabrication
    Microelectrodes
    Peripheral Nervous System
    Neurology
    Central Nervous System
    Substrates

    Keywords

    • MEMS
    • Microelectrode array
    • Microfabrication
    • Neural engineering
    • Neural implant
    • Neural prosthetics

    ASJC Scopus subject areas

    • Biotechnology
    • Bioengineering
    • Molecular Biology

    Cite this

    Microfabricated nerve-electrode interfaces in neural prosthetics and neural engineering. / Song, Rafael; Ibrahim, Ahmed M.S.; Rabie, Amr N.; Han, Jongyoon; Lin, Samuel J.

    In: Biotechnology and Genetic Engineering Reviews, Vol. 29, No. 2, 01.10.2013, p. 113-134.

    Research output: Contribution to journalArticle

    Song, Rafael ; Ibrahim, Ahmed M.S. ; Rabie, Amr N. ; Han, Jongyoon ; Lin, Samuel J. / Microfabricated nerve-electrode interfaces in neural prosthetics and neural engineering. In: Biotechnology and Genetic Engineering Reviews. 2013 ; Vol. 29, No. 2. pp. 113-134.
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