Mechanical property assessment of bone healing around a titanium-zirconium alloy dental implant

Rodolfo B. Anchieta, Marta Baldassarri, Fernando Guastaldi, Nick Tovar, Malvin N. Janal, Jan Gottlow, Michel Dard, Ryo Jimbo, Paulo Coelho

Research output: Contribution to journalArticle

Abstract

Background: It has been reported that titanium-zirconium alloy with 13-17% zirconium (TiZr1317) implants show higher biomechanical stability and bone area percentage relative to commercially pure titanium (cpTi) grade 4 fixtures. Purpose: This study aimed to determine whether the higher stability for TiZr1317 implants is associated with higher mechanical properties of remodeling bone in the areas around the implants. Materials and Methods: This study utilized 36 implants (n=18: TiZr1317, n=18: cpTi), which were placed in the healed ridges of the mandibular premolar and first molar of 12 mini pigs (n=3 implants/animal). After 4 weeks in vivo, the samples were retrieved, and resin-embedded histologic sections of approximately 100μm in thickness were prepared. In order to determine the nanomechanical properties, nanoindentation (n=30 tests/specimen) was performed on the bone tissue of the sections under wet conditions with maximum load of 300μN (loading rate: 60μN/s). Results: The mean (±standard deviation) elastic modulus (E) and hardness (H) for the TiZr1317 group were 2.73±0.50GPa and 0.116±0.017GPa, respectively. For the cpTi group, values were 2.68±0.51GPa and 0.110±0.017GPa for E and H, respectively. Although slightly higher mechanical properties values were observed for the TiZr1317 implants relative to the cpTi for both elastic modulus and hardness, these differences were not significant (E=p>0.75; H=p>0.59). Conclusions: The titanium-zirconium alloy used in this study presented similar degrees of nanomechanical properties to that of the cpTi implants.

Original languageEnglish (US)
Pages (from-to)913-919
Number of pages7
JournalClinical Implant Dentistry and Related Research
DOIs
StatePublished - 2014

Fingerprint

Dental Implants
Titanium
Bone and Bones
Elastic Modulus
Hardness
Bone Remodeling
Bicuspid
Swine

Keywords

  • Animal model
  • Biomechanics
  • Bone
  • Dental/endosteal implants
  • Nanoindentation

ASJC Scopus subject areas

  • Dentistry(all)
  • Oral Surgery

Cite this

Mechanical property assessment of bone healing around a titanium-zirconium alloy dental implant. / Anchieta, Rodolfo B.; Baldassarri, Marta; Guastaldi, Fernando; Tovar, Nick; Janal, Malvin N.; Gottlow, Jan; Dard, Michel; Jimbo, Ryo; Coelho, Paulo.

In: Clinical Implant Dentistry and Related Research, 2014, p. 913-919.

Research output: Contribution to journalArticle

Anchieta, Rodolfo B. ; Baldassarri, Marta ; Guastaldi, Fernando ; Tovar, Nick ; Janal, Malvin N. ; Gottlow, Jan ; Dard, Michel ; Jimbo, Ryo ; Coelho, Paulo. / Mechanical property assessment of bone healing around a titanium-zirconium alloy dental implant. In: Clinical Implant Dentistry and Related Research. 2014 ; pp. 913-919.
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abstract = "Background: It has been reported that titanium-zirconium alloy with 13-17{\%} zirconium (TiZr1317) implants show higher biomechanical stability and bone area percentage relative to commercially pure titanium (cpTi) grade 4 fixtures. Purpose: This study aimed to determine whether the higher stability for TiZr1317 implants is associated with higher mechanical properties of remodeling bone in the areas around the implants. Materials and Methods: This study utilized 36 implants (n=18: TiZr1317, n=18: cpTi), which were placed in the healed ridges of the mandibular premolar and first molar of 12 mini pigs (n=3 implants/animal). After 4 weeks in vivo, the samples were retrieved, and resin-embedded histologic sections of approximately 100μm in thickness were prepared. In order to determine the nanomechanical properties, nanoindentation (n=30 tests/specimen) was performed on the bone tissue of the sections under wet conditions with maximum load of 300μN (loading rate: 60μN/s). Results: The mean (±standard deviation) elastic modulus (E) and hardness (H) for the TiZr1317 group were 2.73±0.50GPa and 0.116±0.017GPa, respectively. For the cpTi group, values were 2.68±0.51GPa and 0.110±0.017GPa for E and H, respectively. Although slightly higher mechanical properties values were observed for the TiZr1317 implants relative to the cpTi for both elastic modulus and hardness, these differences were not significant (E=p>0.75; H=p>0.59). Conclusions: The titanium-zirconium alloy used in this study presented similar degrees of nanomechanical properties to that of the cpTi implants.",
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author = "Anchieta, {Rodolfo B.} and Marta Baldassarri and Fernando Guastaldi and Nick Tovar and Janal, {Malvin N.} and Jan Gottlow and Michel Dard and Ryo Jimbo and Paulo Coelho",
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T1 - Mechanical property assessment of bone healing around a titanium-zirconium alloy dental implant

AU - Anchieta, Rodolfo B.

AU - Baldassarri, Marta

AU - Guastaldi, Fernando

AU - Tovar, Nick

AU - Janal, Malvin N.

AU - Gottlow, Jan

AU - Dard, Michel

AU - Jimbo, Ryo

AU - Coelho, Paulo

PY - 2014

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N2 - Background: It has been reported that titanium-zirconium alloy with 13-17% zirconium (TiZr1317) implants show higher biomechanical stability and bone area percentage relative to commercially pure titanium (cpTi) grade 4 fixtures. Purpose: This study aimed to determine whether the higher stability for TiZr1317 implants is associated with higher mechanical properties of remodeling bone in the areas around the implants. Materials and Methods: This study utilized 36 implants (n=18: TiZr1317, n=18: cpTi), which were placed in the healed ridges of the mandibular premolar and first molar of 12 mini pigs (n=3 implants/animal). After 4 weeks in vivo, the samples were retrieved, and resin-embedded histologic sections of approximately 100μm in thickness were prepared. In order to determine the nanomechanical properties, nanoindentation (n=30 tests/specimen) was performed on the bone tissue of the sections under wet conditions with maximum load of 300μN (loading rate: 60μN/s). Results: The mean (±standard deviation) elastic modulus (E) and hardness (H) for the TiZr1317 group were 2.73±0.50GPa and 0.116±0.017GPa, respectively. For the cpTi group, values were 2.68±0.51GPa and 0.110±0.017GPa for E and H, respectively. Although slightly higher mechanical properties values were observed for the TiZr1317 implants relative to the cpTi for both elastic modulus and hardness, these differences were not significant (E=p>0.75; H=p>0.59). Conclusions: The titanium-zirconium alloy used in this study presented similar degrees of nanomechanical properties to that of the cpTi implants.

AB - Background: It has been reported that titanium-zirconium alloy with 13-17% zirconium (TiZr1317) implants show higher biomechanical stability and bone area percentage relative to commercially pure titanium (cpTi) grade 4 fixtures. Purpose: This study aimed to determine whether the higher stability for TiZr1317 implants is associated with higher mechanical properties of remodeling bone in the areas around the implants. Materials and Methods: This study utilized 36 implants (n=18: TiZr1317, n=18: cpTi), which were placed in the healed ridges of the mandibular premolar and first molar of 12 mini pigs (n=3 implants/animal). After 4 weeks in vivo, the samples were retrieved, and resin-embedded histologic sections of approximately 100μm in thickness were prepared. In order to determine the nanomechanical properties, nanoindentation (n=30 tests/specimen) was performed on the bone tissue of the sections under wet conditions with maximum load of 300μN (loading rate: 60μN/s). Results: The mean (±standard deviation) elastic modulus (E) and hardness (H) for the TiZr1317 group were 2.73±0.50GPa and 0.116±0.017GPa, respectively. For the cpTi group, values were 2.68±0.51GPa and 0.110±0.017GPa for E and H, respectively. Although slightly higher mechanical properties values were observed for the TiZr1317 implants relative to the cpTi for both elastic modulus and hardness, these differences were not significant (E=p>0.75; H=p>0.59). Conclusions: The titanium-zirconium alloy used in this study presented similar degrees of nanomechanical properties to that of the cpTi implants.

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KW - Dental/endosteal implants

KW - Nanoindentation

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