Mechanical properties of human bone surrounding plateau root form implants retrieved after 0.3-24 years of function

Marta Baldassarri, Estevam Bonfante, Marcelo Suzuki, Charles Marin, Rodrigo Granato, Nick Tovar, Paulo Coelho

Research output: Contribution to journalArticle

Abstract

Bone remodeling, along with tissue biomechanics, is critical for the clinical success of endosseous implants. This study evaluated the long-term evolution of the elastic modulus (GPa) and hardness (GPa) of cortical bone around human retrieved plateau root form implants. Thirty implant-in-bone specimens showing no clinical failure were retrieved from patients at different in-vivo times (0.3 to ∼24 years) due to retreatment needs. After dehydration, specimens were embedded in methacrylate-based resin, sectioned along the bucco-lingual long axis and fixed to acrylic plates and nondecalcified processed to slides with ∼50 μm in thickness. Nanoindentation testing was carried out under wet conditions on bone areas within the first three plateaus. Indentations (n = 120 per implant total) were performed with a maximum load of 300 μN (loading rate: 60 μN/s) followed by a holding and unloading time of 10 s and 2 s, respectively. Elastic modulus (E, GPa) and hardness (H, GPa) were computed. Both E and H values presented increased values as time in vivo elapsed (E: r = 0.84; H: r = 0.78). Significantly higher values for E and H were found after 5 years in vivo (p < 0.001). Maxillary or mandibulary arches or positioning did not affect mechanical properties, nor did implant surface treatment on the long-term bone biomechanical response (E: p ≥ 0.09; H: p ≥ 0.3). This work suggests that human cortical bone around plateau root form implants presents an increase in elastic modulus and hardness during the first 5 years following implantation and presents stable mechanical properties thereafter. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2012.

Original languageEnglish (US)
Pages (from-to)2015-2021
Number of pages7
JournalJournal of Biomedical Materials Research - Part B Applied Biomaterials
Volume100 B
Issue number7
DOIs
StatePublished - Oct 2012

Fingerprint

Bone
Mechanical properties
Elastic moduli
Hardness
Long Term Evolution (LTE)
Biomechanics
Methacrylates
Arches
Nanoindentation
Unloading
Dehydration
Indentation
Acrylics
Surface treatment
Resins
Tissue
Testing

Keywords

  • dental implant
  • human retrieval
  • nanoindentation

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biomaterials

Cite this

Mechanical properties of human bone surrounding plateau root form implants retrieved after 0.3-24 years of function. / Baldassarri, Marta; Bonfante, Estevam; Suzuki, Marcelo; Marin, Charles; Granato, Rodrigo; Tovar, Nick; Coelho, Paulo.

In: Journal of Biomedical Materials Research - Part B Applied Biomaterials, Vol. 100 B, No. 7, 10.2012, p. 2015-2021.

Research output: Contribution to journalArticle

Baldassarri, Marta ; Bonfante, Estevam ; Suzuki, Marcelo ; Marin, Charles ; Granato, Rodrigo ; Tovar, Nick ; Coelho, Paulo. / Mechanical properties of human bone surrounding plateau root form implants retrieved after 0.3-24 years of function. In: Journal of Biomedical Materials Research - Part B Applied Biomaterials. 2012 ; Vol. 100 B, No. 7. pp. 2015-2021.
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AB - Bone remodeling, along with tissue biomechanics, is critical for the clinical success of endosseous implants. This study evaluated the long-term evolution of the elastic modulus (GPa) and hardness (GPa) of cortical bone around human retrieved plateau root form implants. Thirty implant-in-bone specimens showing no clinical failure were retrieved from patients at different in-vivo times (0.3 to ∼24 years) due to retreatment needs. After dehydration, specimens were embedded in methacrylate-based resin, sectioned along the bucco-lingual long axis and fixed to acrylic plates and nondecalcified processed to slides with ∼50 μm in thickness. Nanoindentation testing was carried out under wet conditions on bone areas within the first three plateaus. Indentations (n = 120 per implant total) were performed with a maximum load of 300 μN (loading rate: 60 μN/s) followed by a holding and unloading time of 10 s and 2 s, respectively. Elastic modulus (E, GPa) and hardness (H, GPa) were computed. Both E and H values presented increased values as time in vivo elapsed (E: r = 0.84; H: r = 0.78). Significantly higher values for E and H were found after 5 years in vivo (p < 0.001). Maxillary or mandibulary arches or positioning did not affect mechanical properties, nor did implant surface treatment on the long-term bone biomechanical response (E: p ≥ 0.09; H: p ≥ 0.3). This work suggests that human cortical bone around plateau root form implants presents an increase in elastic modulus and hardness during the first 5 years following implantation and presents stable mechanical properties thereafter. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2012.

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