Meat intake and cause-specific mortality: A pooled analysis of Asian prospective cohort studies

Jung Eun Lee, Dale F. McLerran, Betsy Rolland, Yu Chen, Eric J. Grant, Rajesh Vedanthan, Manami Inoue, Shoichiro Tsugane, Yu Tang Gao, Ichiro Tsuji, Masako Kakizaki, Habibul Ahsan, Yoon Ok Ahn, Wen Harn Pan, Kotaro Ozasa, Keun Young Yoo, Shizuka Sasazuki, Gong Yang, Takashi Watanabe, Yumi SugawaraFaruque Parvez, Dong Hyun Kim, Shao Yuan Chuang, Waka Ohishi, Sue K. Park, Ziding Feng, Mark Thornquist, Paolo Boffetta, Wei Zheng, Daehee Kang, John Potter, Rashmi Sinha

Research output: Contribution to journalArticle

Abstract

Background: Total or red meat intake has been shown to be associated with a higher risk of mortality in Western populations, but little is known of the risks in Asian populations Objective: We examined temporal trends in meat consumption and associations between meat intake and all-cause and cause-specific mortality in Asia Design: We used ecological data from the United Nations to compare country-specific meat consumption. Separately, 8 Asian prospective cohort studies in Bangladesh, China, Japan, Korea, and Taiwan consisting of 112,310 men and 184,411 women were followed for 6.6 to 15.6 y with 24,283 all-cause, 9558 cancer, and 6373 cardiovascular disease (CVD) deaths. We estimated the study specific HRs and 95% CIs by using a Cox regression model and pooled them by using a random-effects model Results: Red meat consumption was substantially lower in the Asian countries than in the United States. Fish and seafood consumption was higher in Japan and Korea than in the United States. Our pooled analysis found no association between intake of total meat (red meat, poultry, and fish/seafood) and risks of all-cause, CVD, or cancer mortality among men and women; HRs (95% CIs) for all-cause mortality from a comparison of the highest with the lowest quartile were 1.02 (0.91, 1.15) in men and 0.93 (0.86, 1.01) in women Conclusions: Ecological data indicate an increase in meat intake in Asian countries; however, our pooled analysis did not provide evidence of a higher risk of mortality for total meat intake and provided evidence of an inverse association with red meat, poultry, and fish/seafood. Red meat intake was inversely associated with CVD mortality in men and with cancer mortality in women in Asian countries.

Original languageEnglish (US)
Pages (from-to)1032-1041
Number of pages10
JournalAmerican Journal of Clinical Nutrition
Volume98
Issue number4
DOIs
StatePublished - Oct 1 2013

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Meat
Cohort Studies
Prospective Studies
Mortality
Seafood
Fishes
Cardiovascular Diseases
Poultry
Korea
Japan
Neoplasms
Bangladesh
United Nations
Taiwan
Proportional Hazards Models
Population
China
Red Meat

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Medicine(all)
  • Nutrition and Dietetics

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Meat intake and cause-specific mortality : A pooled analysis of Asian prospective cohort studies. / Lee, Jung Eun; McLerran, Dale F.; Rolland, Betsy; Chen, Yu; Grant, Eric J.; Vedanthan, Rajesh; Inoue, Manami; Tsugane, Shoichiro; Gao, Yu Tang; Tsuji, Ichiro; Kakizaki, Masako; Ahsan, Habibul; Ahn, Yoon Ok; Pan, Wen Harn; Ozasa, Kotaro; Yoo, Keun Young; Sasazuki, Shizuka; Yang, Gong; Watanabe, Takashi; Sugawara, Yumi; Parvez, Faruque; Kim, Dong Hyun; Chuang, Shao Yuan; Ohishi, Waka; Park, Sue K.; Feng, Ziding; Thornquist, Mark; Boffetta, Paolo; Zheng, Wei; Kang, Daehee; Potter, John; Sinha, Rashmi.

In: American Journal of Clinical Nutrition, Vol. 98, No. 4, 01.10.2013, p. 1032-1041.

Research output: Contribution to journalArticle

Lee, JE, McLerran, DF, Rolland, B, Chen, Y, Grant, EJ, Vedanthan, R, Inoue, M, Tsugane, S, Gao, YT, Tsuji, I, Kakizaki, M, Ahsan, H, Ahn, YO, Pan, WH, Ozasa, K, Yoo, KY, Sasazuki, S, Yang, G, Watanabe, T, Sugawara, Y, Parvez, F, Kim, DH, Chuang, SY, Ohishi, W, Park, SK, Feng, Z, Thornquist, M, Boffetta, P, Zheng, W, Kang, D, Potter, J & Sinha, R 2013, 'Meat intake and cause-specific mortality: A pooled analysis of Asian prospective cohort studies', American Journal of Clinical Nutrition, vol. 98, no. 4, pp. 1032-1041. https://doi.org/10.3945/ajcn.113.062638
Lee, Jung Eun ; McLerran, Dale F. ; Rolland, Betsy ; Chen, Yu ; Grant, Eric J. ; Vedanthan, Rajesh ; Inoue, Manami ; Tsugane, Shoichiro ; Gao, Yu Tang ; Tsuji, Ichiro ; Kakizaki, Masako ; Ahsan, Habibul ; Ahn, Yoon Ok ; Pan, Wen Harn ; Ozasa, Kotaro ; Yoo, Keun Young ; Sasazuki, Shizuka ; Yang, Gong ; Watanabe, Takashi ; Sugawara, Yumi ; Parvez, Faruque ; Kim, Dong Hyun ; Chuang, Shao Yuan ; Ohishi, Waka ; Park, Sue K. ; Feng, Ziding ; Thornquist, Mark ; Boffetta, Paolo ; Zheng, Wei ; Kang, Daehee ; Potter, John ; Sinha, Rashmi. / Meat intake and cause-specific mortality : A pooled analysis of Asian prospective cohort studies. In: American Journal of Clinical Nutrition. 2013 ; Vol. 98, No. 4. pp. 1032-1041.
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AU - McLerran, Dale F.

AU - Rolland, Betsy

AU - Chen, Yu

AU - Grant, Eric J.

AU - Vedanthan, Rajesh

AU - Inoue, Manami

AU - Tsugane, Shoichiro

AU - Gao, Yu Tang

AU - Tsuji, Ichiro

AU - Kakizaki, Masako

AU - Ahsan, Habibul

AU - Ahn, Yoon Ok

AU - Pan, Wen Harn

AU - Ozasa, Kotaro

AU - Yoo, Keun Young

AU - Sasazuki, Shizuka

AU - Yang, Gong

AU - Watanabe, Takashi

AU - Sugawara, Yumi

AU - Parvez, Faruque

AU - Kim, Dong Hyun

AU - Chuang, Shao Yuan

AU - Ohishi, Waka

AU - Park, Sue K.

AU - Feng, Ziding

AU - Thornquist, Mark

AU - Boffetta, Paolo

AU - Zheng, Wei

AU - Kang, Daehee

AU - Potter, John

AU - Sinha, Rashmi

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