Maps of visual space in human occipital cortex are retinotopic, not spatiotopic

Justin L. Gardner, Elisha P. Merriam, J. Anthony Movshon, David J. Heeger

Research output: Contribution to journalArticle

Abstract

We experience the visual world as phenomenally invariant to eye position, but almost all cortical maps of visual space in monkeys use a retinotopic reference frame, that is, the cortical representation of a point in the visual world is different across eye positions. It was recently reported that human cortical area MT (unlike monkey MT) represents stimuli in a reference frame linked to the position of stimuli in space, a "spatiotopic" reference frame. We used visuotopic mapping with blood oxygen level-dependent functional magnetic resonance imaging signals to define 12 human visual cortical areas, and then determined whether the reference frame in each area was spatiotopic or retinotopic. We found that all 12 areas, including MT, represented stimuli in a retinotopic reference frame. Although there were patches of cortex in and around these visual areas that were ostensibly spatiotopic, none of these patches exhibited reliable stimulus-evoked responses. We conclude that the early, visuotopically organized visual cortical areas in the human brain (like their counterparts in the monkey brain) represent stimuli in a retinotopic reference frame.

Original languageEnglish (US)
Pages (from-to)3988-3999
Number of pages12
JournalJournal of Neuroscience
Volume28
Issue number15
DOIs
StatePublished - Apr 9 2008

Fingerprint

Occipital Lobe
Haplorhini
Brain
Magnetic Resonance Imaging
Oxygen

Keywords

  • Comparative anatomy
  • Cortex
  • Extrastriate
  • fMRI
  • Reference frame
  • Retinotopy
  • Topography
  • Vision

ASJC Scopus subject areas

  • Neuroscience(all)
  • Medicine(all)

Cite this

Maps of visual space in human occipital cortex are retinotopic, not spatiotopic. / Gardner, Justin L.; Merriam, Elisha P.; Movshon, J. Anthony; Heeger, David J.

In: Journal of Neuroscience, Vol. 28, No. 15, 09.04.2008, p. 3988-3999.

Research output: Contribution to journalArticle

@article{b3fcb22685c04efb91900dbcbbac0f97,
title = "Maps of visual space in human occipital cortex are retinotopic, not spatiotopic",
abstract = "We experience the visual world as phenomenally invariant to eye position, but almost all cortical maps of visual space in monkeys use a retinotopic reference frame, that is, the cortical representation of a point in the visual world is different across eye positions. It was recently reported that human cortical area MT (unlike monkey MT) represents stimuli in a reference frame linked to the position of stimuli in space, a {"}spatiotopic{"} reference frame. We used visuotopic mapping with blood oxygen level-dependent functional magnetic resonance imaging signals to define 12 human visual cortical areas, and then determined whether the reference frame in each area was spatiotopic or retinotopic. We found that all 12 areas, including MT, represented stimuli in a retinotopic reference frame. Although there were patches of cortex in and around these visual areas that were ostensibly spatiotopic, none of these patches exhibited reliable stimulus-evoked responses. We conclude that the early, visuotopically organized visual cortical areas in the human brain (like their counterparts in the monkey brain) represent stimuli in a retinotopic reference frame.",
keywords = "Comparative anatomy, Cortex, Extrastriate, fMRI, Reference frame, Retinotopy, Topography, Vision",
author = "Gardner, {Justin L.} and Merriam, {Elisha P.} and Movshon, {J. Anthony} and Heeger, {David J.}",
year = "2008",
month = "4",
day = "9",
doi = "10.1523/JNEUROSCI.5476-07.2008",
language = "English (US)",
volume = "28",
pages = "3988--3999",
journal = "Journal of Neuroscience",
issn = "0270-6474",
publisher = "Society for Neuroscience",
number = "15",

}

TY - JOUR

T1 - Maps of visual space in human occipital cortex are retinotopic, not spatiotopic

AU - Gardner, Justin L.

AU - Merriam, Elisha P.

AU - Movshon, J. Anthony

AU - Heeger, David J.

PY - 2008/4/9

Y1 - 2008/4/9

N2 - We experience the visual world as phenomenally invariant to eye position, but almost all cortical maps of visual space in monkeys use a retinotopic reference frame, that is, the cortical representation of a point in the visual world is different across eye positions. It was recently reported that human cortical area MT (unlike monkey MT) represents stimuli in a reference frame linked to the position of stimuli in space, a "spatiotopic" reference frame. We used visuotopic mapping with blood oxygen level-dependent functional magnetic resonance imaging signals to define 12 human visual cortical areas, and then determined whether the reference frame in each area was spatiotopic or retinotopic. We found that all 12 areas, including MT, represented stimuli in a retinotopic reference frame. Although there were patches of cortex in and around these visual areas that were ostensibly spatiotopic, none of these patches exhibited reliable stimulus-evoked responses. We conclude that the early, visuotopically organized visual cortical areas in the human brain (like their counterparts in the monkey brain) represent stimuli in a retinotopic reference frame.

AB - We experience the visual world as phenomenally invariant to eye position, but almost all cortical maps of visual space in monkeys use a retinotopic reference frame, that is, the cortical representation of a point in the visual world is different across eye positions. It was recently reported that human cortical area MT (unlike monkey MT) represents stimuli in a reference frame linked to the position of stimuli in space, a "spatiotopic" reference frame. We used visuotopic mapping with blood oxygen level-dependent functional magnetic resonance imaging signals to define 12 human visual cortical areas, and then determined whether the reference frame in each area was spatiotopic or retinotopic. We found that all 12 areas, including MT, represented stimuli in a retinotopic reference frame. Although there were patches of cortex in and around these visual areas that were ostensibly spatiotopic, none of these patches exhibited reliable stimulus-evoked responses. We conclude that the early, visuotopically organized visual cortical areas in the human brain (like their counterparts in the monkey brain) represent stimuli in a retinotopic reference frame.

KW - Comparative anatomy

KW - Cortex

KW - Extrastriate

KW - fMRI

KW - Reference frame

KW - Retinotopy

KW - Topography

KW - Vision

UR - http://www.scopus.com/inward/record.url?scp=43049180245&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=43049180245&partnerID=8YFLogxK

U2 - 10.1523/JNEUROSCI.5476-07.2008

DO - 10.1523/JNEUROSCI.5476-07.2008

M3 - Article

VL - 28

SP - 3988

EP - 3999

JO - Journal of Neuroscience

JF - Journal of Neuroscience

SN - 0270-6474

IS - 15

ER -