Mapping the chemistry of highly unsaturated pyrone polyketides

Aubry K. Miller, Dirk Trauner

Research output: Contribution to journalArticle

Abstract

Highly unsaturated pyrone polyketides ('HUPPs') are a growing family of natural products derived from polyene precursors, often through pericyclic or ionic reaction cascades. We describe our extensive studies on this class of compounds, which have so far resulted in the total synthesis of 17 of its members.

Original languageEnglish (US)
Pages (from-to)2295-2316
Number of pages22
JournalSynlett
Issue number14
DOIs
StatePublished - Sep 1 2006

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Pyrones
Polyketides
Polyenes
Biological Products

Keywords

  • Biomimetic synthesis
  • Cross-couplings
  • Electrocyclic reactions
  • Natural products
  • Reaction cascades

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Mapping the chemistry of highly unsaturated pyrone polyketides. / Miller, Aubry K.; Trauner, Dirk.

In: Synlett, No. 14, 01.09.2006, p. 2295-2316.

Research output: Contribution to journalArticle

Miller, Aubry K. ; Trauner, Dirk. / Mapping the chemistry of highly unsaturated pyrone polyketides. In: Synlett. 2006 ; No. 14. pp. 2295-2316.
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