Mapping hV4 and ventral occipital cortex: The venous eclipse

Jonathan Winawer, Hiroshi Horiguchi, Rory A. Sayres, Kaoru Amano, Brian A. Wandell

Research output: Contribution to journalArticle

Abstract

While the fourth human visual field map (hV4) has been studied for two decades, there remain uncertainties about its spatial organization. In analyzing fMRI measurements designed to resolve these issues, we discovered a significant problem that afflicts measurements from ventral occipital cortex, and particularly measurements near hV4. In most hemispheres the fMRI hV4 data are contaminated by artifacts from the transverse sinus (TS). We created a model of the TS artifact and showed that the model predicts the locations of anomalous fMRI responses to simple large-field on-off stimuli. In many subjects, and particularly the left hemisphere, the TS artifact masks fMRI responses specifically in the region of cortex that distinguishes the two main hV4 models. By selecting subjects with a TS displaced from the lateral edge of hV4, we were able to see around the vein. In these subjects, the visual field coverage extends to the lower meridian, or nearly so, consistent with a model in which hV4 is located on the ventral surface and responds to signals throughout the full contralateral hemifield.

Original languageEnglish (US)
Pages (from-to)1-22
Number of pages22
JournalJournal of Vision
Volume10
Issue number5
DOIs
StatePublished - 2010

Fingerprint

Transverse Sinuses
Occipital Lobe
Magnetic Resonance Imaging
Artifacts
Visual Fields
Meridians
Masks
Uncertainty
Veins

Keywords

  • Fmri
  • Functional imaging
  • Occipital cortex
  • Receptive fields
  • V4

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Medicine(all)

Cite this

Winawer, J., Horiguchi, H., Sayres, R. A., Amano, K., & Wandell, B. A. (2010). Mapping hV4 and ventral occipital cortex: The venous eclipse. Journal of Vision, 10(5), 1-22. https://doi.org/10.1167/10.5.1

Mapping hV4 and ventral occipital cortex : The venous eclipse. / Winawer, Jonathan; Horiguchi, Hiroshi; Sayres, Rory A.; Amano, Kaoru; Wandell, Brian A.

In: Journal of Vision, Vol. 10, No. 5, 2010, p. 1-22.

Research output: Contribution to journalArticle

Winawer, J, Horiguchi, H, Sayres, RA, Amano, K & Wandell, BA 2010, 'Mapping hV4 and ventral occipital cortex: The venous eclipse', Journal of Vision, vol. 10, no. 5, pp. 1-22. https://doi.org/10.1167/10.5.1
Winawer J, Horiguchi H, Sayres RA, Amano K, Wandell BA. Mapping hV4 and ventral occipital cortex: The venous eclipse. Journal of Vision. 2010;10(5):1-22. https://doi.org/10.1167/10.5.1
Winawer, Jonathan ; Horiguchi, Hiroshi ; Sayres, Rory A. ; Amano, Kaoru ; Wandell, Brian A. / Mapping hV4 and ventral occipital cortex : The venous eclipse. In: Journal of Vision. 2010 ; Vol. 10, No. 5. pp. 1-22.
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