Macroscopic modeling and simulations of supercoiled DNA with bound proteins

Jing Huang, Tamar Schlick

Research output: Contribution to journalArticle

Abstract

A polymer-level computational model and simulation protocols for supercoiled DNA molecules was developed. The resultant model incorporates the electrostatic and structural properties of DNA molecules with bound proteins based on the well established discrete wormlike chain model for supercoiled DNA.

Original languageEnglish (US)
Pages (from-to)8573-8586
Number of pages14
JournalJournal of Chemical Physics
Volume117
Issue number18
DOIs
StatePublished - Nov 8 2002

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Superhelical DNA
deoxyribonucleic acid
proteins
Proteins
Molecules
simulation
Structural properties
molecules
Electrostatics
Polymers
electrostatics
DNA
polymers

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Macroscopic modeling and simulations of supercoiled DNA with bound proteins. / Huang, Jing; Schlick, Tamar.

In: Journal of Chemical Physics, Vol. 117, No. 18, 08.11.2002, p. 8573-8586.

Research output: Contribution to journalArticle

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