Low-frequency cortical oscillations entrain to subthreshold rhythmic auditory stimuli

Sanne Ten Oever, Charles E. Schroeder, David Poeppel, Nienke Van Atteveldt, Ashesh D. Mehta, Pierre Mégevand, David M. Groppe, Elana Zion-Golumbic

Research output: Contribution to journalArticle

Abstract

Many environmental stimuli contain temporal regularities, a feature that can help predict forthcoming input. Phase locking (entrainment) of ongoing low-frequency neuronal oscillations to rhythmic stimuli is proposed as a potential mechanism for enhancing neuronal responses and perceptual sensitivity, by aligning high-excitability phases to events within a stimulus stream. Previous experiments show that rhythmic structure has a behavioral benefit even when the rhythm itself is below perceptual detection thresholds (ten Oever et al., 2014). It is not known whether this “inaudible” rhythmic sound stream also induces entrainment. Here we tested this hypothesis using magnetoencephalography and electrocorticography in humans to record changes in neuronal activity as subthreshold rhythmic stimuli gradually became audible. We found that significant phase locking to the rhythmic sounds preceded participants’ detection of them. Moreover, no significant auditory-evoked responses accompanied this prethreshold entrainment. These auditory-evoked responses, distinguished by robust, broad-band increases in intertrial coherence, only appeared after sounds were reported as audible. Taken together with the reduced perceptual thresholds observed for rhythmic sequences, these findings support the proposition that entrainment of low-frequency oscillations serves a mechanistic role in enhancing perceptual sensitivity for temporally predictive sounds. This framework has broad implications for understanding the neural mechanisms involved in generating temporal predictions and their relevance for perception, attention, and awareness.

Original languageEnglish (US)
Pages (from-to)4903-4912
Number of pages10
JournalJournal of Neuroscience
Volume37
Issue number19
DOIs
StatePublished - May 10 2017

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Auditory Evoked Potentials
Magnetoencephalography
Electrocorticography

Keywords

  • Auditory
  • Detection
  • ECoG
  • Entrainment
  • MEG
  • Oscillations

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Ten Oever, S., Schroeder, C. E., Poeppel, D., Van Atteveldt, N., Mehta, A. D., Mégevand, P., ... Zion-Golumbic, E. (2017). Low-frequency cortical oscillations entrain to subthreshold rhythmic auditory stimuli. Journal of Neuroscience, 37(19), 4903-4912. https://doi.org/10.1523/JNEUROSCI.3658-16.2017

Low-frequency cortical oscillations entrain to subthreshold rhythmic auditory stimuli. / Ten Oever, Sanne; Schroeder, Charles E.; Poeppel, David; Van Atteveldt, Nienke; Mehta, Ashesh D.; Mégevand, Pierre; Groppe, David M.; Zion-Golumbic, Elana.

In: Journal of Neuroscience, Vol. 37, No. 19, 10.05.2017, p. 4903-4912.

Research output: Contribution to journalArticle

Ten Oever, S, Schroeder, CE, Poeppel, D, Van Atteveldt, N, Mehta, AD, Mégevand, P, Groppe, DM & Zion-Golumbic, E 2017, 'Low-frequency cortical oscillations entrain to subthreshold rhythmic auditory stimuli', Journal of Neuroscience, vol. 37, no. 19, pp. 4903-4912. https://doi.org/10.1523/JNEUROSCI.3658-16.2017
Ten Oever, Sanne ; Schroeder, Charles E. ; Poeppel, David ; Van Atteveldt, Nienke ; Mehta, Ashesh D. ; Mégevand, Pierre ; Groppe, David M. ; Zion-Golumbic, Elana. / Low-frequency cortical oscillations entrain to subthreshold rhythmic auditory stimuli. In: Journal of Neuroscience. 2017 ; Vol. 37, No. 19. pp. 4903-4912.
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