Longitudinal associations of leisure-time physical activity and cancer mortality in the Third National Health and Nutrition Examination Survey (1986-2006)

Niyati Parekh, Yong Lin, Lynette L. Craft, Maya Vadiveloo, Grace L. Lu-Yao

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Abstract

Longitudinal associations between leisure-time physical activity (LTPA) and overall cancer mortality were evaluated within the Third National Health and Nutrition Examination Survey (NHANES III; 1988-2006; n = 15,535). Mortality status was ascertained using the National Death Index. Self-reported LTPA was divided into inactive, regular low-to-moderate and vigorous activity. A frequency-weighted metabolic equivalents (METS/week) variable was also computed. Hazard ratios (HRs) and 95 confidence intervals (CI) were calculated for overall cancer mortality in the whole sample, by body mass index categories and insulin resistance (IR) status. Nonsignificant protective associations were observed for regular low-to-moderate and vigorous activity, and for the highest quartile of METS/week (HRs range: 0.66-0.95). Individuals without IR engaging in regular vigorous activity had a 48 decreased risk of cancer mortality (HR: 0.52; 95 CI: 0.28-0.98) in multivariate analyses. Conversely, nonsignificant positive associations were observed in people with IR. In conclusion, regular vigorous activity may reduce risk of cancer mortality among persons with normal insulin-glucose metabolism in this national sample.

Original languageEnglish (US)
Article number518358
JournalJournal of Obesity
Volume2012
DOIs
StatePublished - 2012

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Nutrition Surveys
Leisure Activities
Mortality
Insulin Resistance
Neoplasms
Metabolic Equivalent
Confidence Intervals
Body Mass Index
Multivariate Analysis
Insulin
Glucose

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism

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Longitudinal associations of leisure-time physical activity and cancer mortality in the Third National Health and Nutrition Examination Survey (1986-2006). / Parekh, Niyati; Lin, Yong; Craft, Lynette L.; Vadiveloo, Maya; Lu-Yao, Grace L.

In: Journal of Obesity, Vol. 2012, 518358, 2012.

Research output: Contribution to journalArticle

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AU - Lu-Yao, Grace L.

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