Long lived NMR signal in bone

Boyang Zhang, Jae Seung Lee, Anatoly Khitrin, Alexej Jerschow

Research output: Contribution to journalArticle

Abstract

Solids and rigid tissues, such as bone, ligaments, and tendons, typically appear dark in MRI, which is due to the extremely short-lived proton nuclear magnetic resonance signals. This short lifetime is due to strong dipolar interactions between immobilized proton spins, which render it challenging to detect these signals with sufficient resolution and sensitivity. Here we show the possibility of exciting long-lived signals in cortical bone tissue with a signature consistent with that of bound water signals. It is further shown that dipolar coupling networks are an integral requirement for the excitation of these long-lived signals. The use of these signals could enhance the ability to visualize rigid tissues and solid samples with high resolution and sensitivity via MRI.

Original languageEnglish (US)
Pages (from-to)1-4
Number of pages4
JournalJournal of Magnetic Resonance
Volume231
DOIs
StatePublished - Jun 2013

Fingerprint

bones
Protons
Bone
Nuclear magnetic resonance
Tissue
Bone and Bones
Magnetic resonance imaging
nuclear magnetic resonance
Ligaments
Tendons
Magnetic Resonance Spectroscopy
Water
tendons
ligaments
proton magnetic resonance
sensitivity
signatures
life (durability)
requirements
protons

Keywords

  • Bone
  • Dipolar coupling
  • Homogeneous broadening
  • Long-lived signals
  • MRI

ASJC Scopus subject areas

  • Nuclear and High Energy Physics
  • Biochemistry
  • Biophysics
  • Condensed Matter Physics

Cite this

Long lived NMR signal in bone. / Zhang, Boyang; Lee, Jae Seung; Khitrin, Anatoly; Jerschow, Alexej.

In: Journal of Magnetic Resonance, Vol. 231, 06.2013, p. 1-4.

Research output: Contribution to journalArticle

Zhang, Boyang ; Lee, Jae Seung ; Khitrin, Anatoly ; Jerschow, Alexej. / Long lived NMR signal in bone. In: Journal of Magnetic Resonance. 2013 ; Vol. 231. pp. 1-4.
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