Localization of polymorphic DNA probes frequently deleted in lung carcinoma

Donna Albertson, Paul D. Sherrington, Pamela H. Rabbitts

Research output: Contribution to journalArticle

Abstract

Five polymorphic DNA segments from human chromosome 3, that are frequently deleted in lung carcinoma were mapped by non-isotopic in situ hybridization to metaphase chromosomes. The DNA segment D3S3 mapped to 3p13-p14.2, D3S6 to 3p14.3-p14.5, D3S48 to distal 3p21-p22, ERBAß to 3p24.3 and ERBA2 to 3p24.3. The map location of ERBAß and ERBA2 was confirmed by re-mapping each probe in combination with D3S6 as a marker for 3p14.

Original languageEnglish (US)
Pages (from-to)127-132
Number of pages6
JournalHuman Genetics
Volume83
Issue number2
DOIs
StatePublished - Sep 1989

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DNA Probes
Carcinoma
Lung
Chromosomes, Human, Pair 3
DNA
Human Chromosomes
Metaphase
In Situ Hybridization
Chromosomes

ASJC Scopus subject areas

  • Genetics(clinical)
  • Genetics

Cite this

Localization of polymorphic DNA probes frequently deleted in lung carcinoma. / Albertson, Donna; Sherrington, Paul D.; Rabbitts, Pamela H.

In: Human Genetics, Vol. 83, No. 2, 09.1989, p. 127-132.

Research output: Contribution to journalArticle

Albertson, Donna ; Sherrington, Paul D. ; Rabbitts, Pamela H. / Localization of polymorphic DNA probes frequently deleted in lung carcinoma. In: Human Genetics. 1989 ; Vol. 83, No. 2. pp. 127-132.
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