Local cerebral blood flow increases during auditory and emotional processing in the conscious rat

Joseph Ledoux, M. E. Thompson, C. Iadecola, L. W. Tucker, D. J. Reis

Research output: Contribution to journalArticle

Abstract

Local cerebral blood flow was measured in rats by the 14C-labeled iodoantipyrine technique with quantitative autoradiography during the processing of environmental stimuli. Presentation of a tone increased blood flow in the auditory but not the visual pathway. When the animal had previously been conditioned to fear the tone, blood flow additionally increased in the hypothalamus and amygdala. Local cerebral blood flow can thus be used to detect patterns of cerebral excitation associated with transient (30- to 40-second) mental events in experimental animals.

Original languageEnglish (US)
Pages (from-to)576-578
Number of pages3
JournalScience
Volume221
Issue number4610
DOIs
StatePublished - 1983

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Cerebrovascular Circulation
Visual Pathways
Amygdala
Autoradiography
Hypothalamus
Fear

ASJC Scopus subject areas

  • General

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Local cerebral blood flow increases during auditory and emotional processing in the conscious rat. / Ledoux, Joseph; Thompson, M. E.; Iadecola, C.; Tucker, L. W.; Reis, D. J.

In: Science, Vol. 221, No. 4610, 1983, p. 576-578.

Research output: Contribution to journalArticle

Ledoux, Joseph ; Thompson, M. E. ; Iadecola, C. ; Tucker, L. W. ; Reis, D. J. / Local cerebral blood flow increases during auditory and emotional processing in the conscious rat. In: Science. 1983 ; Vol. 221, No. 4610. pp. 576-578.
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