Lipid composition and biosynthesis in the gingiva of the domestic cat.

J. L. Rabinowitz, O. Sheridan, Ronald Craig, R. Feldman, E. R. Grossman, C. E. Harvey, M. E. Haskins

Research output: Contribution to journalArticle

Abstract

Periodontal disease in the domestic cat may assume debilitating and serious consequences; however, little is known of the biochemical composition or metabolism of feline gingiva in health or disease. In this report the chemical composition and metabolism of gingival lipids from inflamed an non-inflamed sites is presented and compared to other species with naturally occurring periodontitis. The neutral and phospholipid composition of feline gingiva was found to be distinct from that of porcine and human. As a measure of de novo lipid synthesis, the total incorporation of 14C-acetate into fractionated lipid components was determined and revealed an approximate 2 to 3 fold decrease in inflamed versus non-inflamed gingiva. The decrease in 14C-acetate incorporation appeared to result from a 2-fold increase in free acetate pools in inflamed compared to non-inflamed gingival samples, since total lipase and phospholipase activity were comparable in inflamed and non-inflamed gingiva and total lipid composition was not changed between inflamed and non-inflamed sites. These data are similar to those reported for periodontally involved human gingival tissue and suggest a common effect of periodontal inflammation on lipid metabolism in both species.

Original languageEnglish (US)
Pages (from-to)495-498
Number of pages4
JournalJournal of Periodontology
Volume62
Issue number8
StatePublished - Aug 1991

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Gingiva
Cats
Lipids
Acetates
Felidae
Lipid Metabolism
Phospholipases
Periodontitis
Periodontal Diseases
Lipase
Phospholipids
Swine
Inflammation
Health

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Rabinowitz, J. L., Sheridan, O., Craig, R., Feldman, R., Grossman, E. R., Harvey, C. E., & Haskins, M. E. (1991). Lipid composition and biosynthesis in the gingiva of the domestic cat. Journal of Periodontology, 62(8), 495-498.

Lipid composition and biosynthesis in the gingiva of the domestic cat. / Rabinowitz, J. L.; Sheridan, O.; Craig, Ronald; Feldman, R.; Grossman, E. R.; Harvey, C. E.; Haskins, M. E.

In: Journal of Periodontology, Vol. 62, No. 8, 08.1991, p. 495-498.

Research output: Contribution to journalArticle

Rabinowitz, JL, Sheridan, O, Craig, R, Feldman, R, Grossman, ER, Harvey, CE & Haskins, ME 1991, 'Lipid composition and biosynthesis in the gingiva of the domestic cat.', Journal of Periodontology, vol. 62, no. 8, pp. 495-498.
Rabinowitz JL, Sheridan O, Craig R, Feldman R, Grossman ER, Harvey CE et al. Lipid composition and biosynthesis in the gingiva of the domestic cat. Journal of Periodontology. 1991 Aug;62(8):495-498.
Rabinowitz, J. L. ; Sheridan, O. ; Craig, Ronald ; Feldman, R. ; Grossman, E. R. ; Harvey, C. E. ; Haskins, M. E. / Lipid composition and biosynthesis in the gingiva of the domestic cat. In: Journal of Periodontology. 1991 ; Vol. 62, No. 8. pp. 495-498.
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