Lip cancer: Incidence trends in Connecticut, 1935-1985

J. Chen, Ralph Katz, D. J. Krutchkoff, E. Eisenberg

Research output: Contribution to journalArticle

Abstract

Suspicions have recently arisen that cancer of the lip may exert an undue influence on overall oral cancer statistics and, therefore, possibly distort the true image of intraoral cancer. The authors investigated this question through epidemiologic analysis. A total of 2291 cases of lip cancer accessioned by the Connecticut Tumor Registry (CTR) from 1935 to 1985 (23.6% of all oral cancer) were analyzed. Occurrence trends for males and females had different patterns: for men, the age-adjusted incidence rates showed a fivefold decrease during the 51-year study; for women, the rates were relatively low and constant during the same period. Analysis for age-specific rates revealed that the older the age group, the higher the incidence rates for both sexes. Squamous cell carcinoma accounted for at least 87.4% of all lip cancers (96.2% if nonspecified epithelial neoplasms are assumed to be squamous cell carcinoma). The vermilion border of lower lip was the most common site. Moderately differentiated tumors were most common (48.5%), closely followed by well-differentiated tumors (44.2%). Analysis by county showed that the crude incidence rates for males in New London and Windham counties exceeded the average Connecticut statewide rates. The authors concluded that the epidemiology of Connecticut lip cancer differs significantly from that of intraoral squamous cell carcinoma in the same population studied within the same period of time. Epidemiologic studies involving 'oral cancer' should direct attention to anatomic subsite to consider differences in disease trends according to specific location.

Original languageEnglish (US)
Pages (from-to)2025-2030
Number of pages6
JournalCancer
Volume70
Issue number8
DOIs
StatePublished - 1992

Fingerprint

Lip Neoplasms
Mouth Neoplasms
Squamous Cell Carcinoma
Incidence
Neoplasms
Glandular and Epithelial Neoplasms
Lip
Registries
Epidemiologic Studies
Epidemiology
Age Groups
Population

Keywords

  • epidemiology
  • lip
  • lip cancer
  • oral cancer
  • squamous cell carcinoma

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Lip cancer : Incidence trends in Connecticut, 1935-1985. / Chen, J.; Katz, Ralph; Krutchkoff, D. J.; Eisenberg, E.

In: Cancer, Vol. 70, No. 8, 1992, p. 2025-2030.

Research output: Contribution to journalArticle

Chen, J. ; Katz, Ralph ; Krutchkoff, D. J. ; Eisenberg, E. / Lip cancer : Incidence trends in Connecticut, 1935-1985. In: Cancer. 1992 ; Vol. 70, No. 8. pp. 2025-2030.
@article{c09d9d1179944b6a90a8beb1d1a3ef07,
title = "Lip cancer: Incidence trends in Connecticut, 1935-1985",
abstract = "Suspicions have recently arisen that cancer of the lip may exert an undue influence on overall oral cancer statistics and, therefore, possibly distort the true image of intraoral cancer. The authors investigated this question through epidemiologic analysis. A total of 2291 cases of lip cancer accessioned by the Connecticut Tumor Registry (CTR) from 1935 to 1985 (23.6{\%} of all oral cancer) were analyzed. Occurrence trends for males and females had different patterns: for men, the age-adjusted incidence rates showed a fivefold decrease during the 51-year study; for women, the rates were relatively low and constant during the same period. Analysis for age-specific rates revealed that the older the age group, the higher the incidence rates for both sexes. Squamous cell carcinoma accounted for at least 87.4{\%} of all lip cancers (96.2{\%} if nonspecified epithelial neoplasms are assumed to be squamous cell carcinoma). The vermilion border of lower lip was the most common site. Moderately differentiated tumors were most common (48.5{\%}), closely followed by well-differentiated tumors (44.2{\%}). Analysis by county showed that the crude incidence rates for males in New London and Windham counties exceeded the average Connecticut statewide rates. The authors concluded that the epidemiology of Connecticut lip cancer differs significantly from that of intraoral squamous cell carcinoma in the same population studied within the same period of time. Epidemiologic studies involving 'oral cancer' should direct attention to anatomic subsite to consider differences in disease trends according to specific location.",
keywords = "epidemiology, lip, lip cancer, oral cancer, squamous cell carcinoma",
author = "J. Chen and Ralph Katz and Krutchkoff, {D. J.} and E. Eisenberg",
year = "1992",
doi = "10.1002/1097-0142(19921015)70:8<2025::AID-CNCR2820700802>3.0.CO;2-4",
language = "English (US)",
volume = "70",
pages = "2025--2030",
journal = "Cancer",
issn = "0008-543X",
publisher = "John Wiley and Sons Inc.",
number = "8",

}

TY - JOUR

T1 - Lip cancer

T2 - Incidence trends in Connecticut, 1935-1985

AU - Chen, J.

AU - Katz, Ralph

AU - Krutchkoff, D. J.

AU - Eisenberg, E.

PY - 1992

Y1 - 1992

N2 - Suspicions have recently arisen that cancer of the lip may exert an undue influence on overall oral cancer statistics and, therefore, possibly distort the true image of intraoral cancer. The authors investigated this question through epidemiologic analysis. A total of 2291 cases of lip cancer accessioned by the Connecticut Tumor Registry (CTR) from 1935 to 1985 (23.6% of all oral cancer) were analyzed. Occurrence trends for males and females had different patterns: for men, the age-adjusted incidence rates showed a fivefold decrease during the 51-year study; for women, the rates were relatively low and constant during the same period. Analysis for age-specific rates revealed that the older the age group, the higher the incidence rates for both sexes. Squamous cell carcinoma accounted for at least 87.4% of all lip cancers (96.2% if nonspecified epithelial neoplasms are assumed to be squamous cell carcinoma). The vermilion border of lower lip was the most common site. Moderately differentiated tumors were most common (48.5%), closely followed by well-differentiated tumors (44.2%). Analysis by county showed that the crude incidence rates for males in New London and Windham counties exceeded the average Connecticut statewide rates. The authors concluded that the epidemiology of Connecticut lip cancer differs significantly from that of intraoral squamous cell carcinoma in the same population studied within the same period of time. Epidemiologic studies involving 'oral cancer' should direct attention to anatomic subsite to consider differences in disease trends according to specific location.

AB - Suspicions have recently arisen that cancer of the lip may exert an undue influence on overall oral cancer statistics and, therefore, possibly distort the true image of intraoral cancer. The authors investigated this question through epidemiologic analysis. A total of 2291 cases of lip cancer accessioned by the Connecticut Tumor Registry (CTR) from 1935 to 1985 (23.6% of all oral cancer) were analyzed. Occurrence trends for males and females had different patterns: for men, the age-adjusted incidence rates showed a fivefold decrease during the 51-year study; for women, the rates were relatively low and constant during the same period. Analysis for age-specific rates revealed that the older the age group, the higher the incidence rates for both sexes. Squamous cell carcinoma accounted for at least 87.4% of all lip cancers (96.2% if nonspecified epithelial neoplasms are assumed to be squamous cell carcinoma). The vermilion border of lower lip was the most common site. Moderately differentiated tumors were most common (48.5%), closely followed by well-differentiated tumors (44.2%). Analysis by county showed that the crude incidence rates for males in New London and Windham counties exceeded the average Connecticut statewide rates. The authors concluded that the epidemiology of Connecticut lip cancer differs significantly from that of intraoral squamous cell carcinoma in the same population studied within the same period of time. Epidemiologic studies involving 'oral cancer' should direct attention to anatomic subsite to consider differences in disease trends according to specific location.

KW - epidemiology

KW - lip

KW - lip cancer

KW - oral cancer

KW - squamous cell carcinoma

UR - http://www.scopus.com/inward/record.url?scp=0026783510&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026783510&partnerID=8YFLogxK

U2 - 10.1002/1097-0142(19921015)70:8<2025::AID-CNCR2820700802>3.0.CO;2-4

DO - 10.1002/1097-0142(19921015)70:8<2025::AID-CNCR2820700802>3.0.CO;2-4

M3 - Article

C2 - 1394031

AN - SCOPUS:0026783510

VL - 70

SP - 2025

EP - 2030

JO - Cancer

JF - Cancer

SN - 0008-543X

IS - 8

ER -